Results 131 to 140 of about 5,459,787 (328)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Simple signage and targeted education can lead to process improvement in acute appendicitis care. [PDF]

open access: yesBMJ Open Qual, 2023
Atwood R   +8 more
europepmc   +1 more source

Place of technology management as a key process area within construction process improvement: A critical analysis [PDF]

open access: yes
Process improvement has been identified as an important strategy to address the current unpredictability and under-achievements of the UK construction industry.
Amaratunga, Dilanthi   +2 more
core  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Risk Management Practices in the Purchasing System of an Automotive Company

open access: yesSystems
This paper presents the results of a case study conducted in the purchasing department of Bosch Car Multimedia Portugal, aiming to analyze and improve risk management practices within its project environment. Projects in this department are characterized
Anabela Tereso   +2 more
doaj   +1 more source

Influence of the autochthonous cellulolytic bacteria on the domestic compost process improvement. [PDF]

open access: yesBioTechnologia (Pozn), 2023
Ćwiertniewicz-Wojciechowska M   +3 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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