Results 171 to 180 of about 25,679,349 (377)
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Quality and process improvement of the multidisciplinary Heart Team meeting using Lean Six Sigma. [PDF]
BMJ Open Qual, 2023 Hoefsmit PC +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Making a Sustainable Difference to People, Processes and Systems: Whole-Systems Approaches to Process Improvement in Health Systems. [PDF]
Int J Environ Res Public Health, 2023 McNamara M, Ward M, Teeling SP.
europepmc +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
A systematic review of the evidence of how hospitals capture financial benefits of process improvement and the impact on hospital financial performance. [PDF]
BMC Health Serv Res, 2023 Evans J, Leggat SG, Samson D.
europepmc +1 more source