Results 61 to 70 of about 791,980 (219)

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Surrendering to the Process: Innovation in Developing CPD for General Practice. [PDF]

open access: yesJ CME, 2023
Vestergaard SK   +3 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Unlocking the potential of trace cobalt in Ni-based superalloys: A molecular dynamics study on dislocation behavior and high-temperature stability

open access: yesMaterials & Design
Cobalt (Co) is one of the fastest diffusing elements in Nickel (Ni)-based single crystal superalloys, playing a critical role in stabilizing the γ matrix and γ′ precipitate, and influencing dislocation behavior and deformation mechanisms.
Huicong Dong   +5 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

New Strategy for Microbial Corrosion Protection: Photocatalytic Antimicrobial Quantum Dots

open access: yesNanomaterials
Microbial corrosion has significant implications for the economy, environment, and human safety worldwide. Photocatalytic antibacterial technology, owing to its advantages in environmental protection, broad-spectrum, and efficient sterilization, presents
Shijia Liu   +7 more
doaj   +1 more source

Digital Processes for the Redevelopment of Social Housing in Plattenbau

open access: yesAgathón, 2019
As part of a framework agreement between the DiARC of the ‘Federico II’ University of Naples and the Fakultät Bauwesen of the HTWK Leipzig, which led to a collaboration with the LWB – the public housing manager of the city of Leipzig which for years has ...
Marina Block   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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