Results 71 to 80 of about 21,952,323 (349)

Designing transition paths for the diffusion of sustainable system innovations. A new potential role for design in transition management? [PDF]

open access: yes, 2008
Copyright @ 2008 Umberto AllemandiIt is a shared opinion that the transition towards sustainability will be a continuous and articulated learning process, which will require radical changes on multiple levels (social, cultural, institutional and ...
Ceschin, F, Kemp, R, Vezzoli, C
core  

Alloy development and process innovations for light metals casting

open access: yesJournal of Materials Processing Technology, 2022
A. Luo, A. Sachdev, D. Apelian
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Notes on interdiction in the Civil Procedure Code of 2015 (part 1)

open access: yesRevista Eletrônica de Direito Processual, 2015
This study covers the procedure for interdiction of persons (declaration of mental or physical incapacity) under the Civil Procedure Code of 2015, highlighting its main innovations.
Leonardo Faria Schenk
doaj   +1 more source

Making use of digital innovations in Business Process Improvements [PDF]

open access: yesDatabase Systems Journal, 2023
Business Process Management (BPM) concept is more and more influenced by the emerging technologies changing the conventional way of improving or optimizing the business processes.
Radu SAMOILA
doaj  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Protein Polarimetry, Perfected: Specific Rotation Measurement for the Refracto-Polarimetric Detection of Cryptic Protein Denaturation

open access: yesBiophysica
Protein polarimetry has been evaluated as a simple and straightforward technique to detect the cryptic denaturation of exemplary proteins. The general rules of rotation vs.
Lisa Riedlsperger   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Hybrid MOF+COF modified PVDF membranes for enhanced microfiltration of pharmaceutical contaminants

open access: yesWater Resources and Industry
One of the key directions in membrane process development is the exploration of novel materials and the modification of commonly used ones. Designing membrane structures with programmable properties enhances process efficiency and broadens application ...
Daniel Polak   +4 more
doaj   +1 more source

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