Results 111 to 120 of about 72,470 (313)
Local and global process intensification
, 2014 International audienceThe present paper aims at proposing a complementary view of process intensification (PI) based on the concepts of local intensification and global intensification.
Falk, Laurent +2 more
core +1 more source
INTENSIFICATION OF THE LEGISLATIVE PROCESS:
Gênero & Direito, 2020 The article presents an analysis of the legislative process in the Republic of Serbia. The leading method in this study is a systematic approach that allowed analyzing the specifics of the stages of the legislative process in terms of ensuring its effectiveness and efficiency.
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Systematic process intensification
Current Opinion in Chemical Engineering, 2019 Process intensification often requires innovative equipment and flowsheets to achieve significant improvement compared to traditional unit operations. Systematic methods are needed for automatic generation, screening, and discovery of promising intensification pathways at the conceptual design stage.
Salih Emre Demirel +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Process intensification in the continuous dehydrogenation of methylcyclohexane to toluene
Publisher Copyright: © 2024The toluene/methylcyclohexane cycle is a safe and practical Liquid Organic Hydrogen Carrier (LOHC) for the storage of hydrogen.
Madurga, Belén Maestro +3 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Ultrasonics SonochemistryExtracting polyphenolic bioactive compounds from Pinus elliottii needles, a forestry residue, promises economic and environmental benefits, however, relevant experimental data are lacking.
Siheng Zhang +7 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source