Results 131 to 140 of about 323,824 (292)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Division intensification according to fineness and dehydration of raw materials at the new way of vibroshock grating [PDF]

, 2013
Наведено результати експериментальних досліджень нового методу віброударного грохочення з використанням для інтенсифікації розпушення крупних часток. Отримано залежності вологості надрешітного і та вмісту класів у продуктах від співвідношення крупних ...
Shevchenko, А.I.
core  

Space-constrained purification of dimethyl ether through process intensification using semicontinuous dividing wall columns [PDF]

, 2017
Sarah Ballinger, Thomas A. Adams
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Heat transfer characteristics of hydrid microjet-microchannel cooling module [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Andrzejczyk, R, Muszynski, T   +2 more
core  

Process Intensification of a Napabucasin Manufacturing Method Utilizing Microflow Chemistry. [PDF]

ACS Omega, 2023
Usutani H, Yamamoto K, Hashimoto K.
europepmc   +1 more source

Process intensification in multicomponent distillation: A review of recent advancements

, 2019
Zheyu Jiang, Rakesh Agrawal
openalex   +2 more sources

LINGUODIDACTIC BASES OF INTENSIFYING THE PROCESS OF TEACHING FOREIGN LANGUAGES TO STUDENTS AT NONLINGUISTIC HIGHER EDUCATION INSTITUTIONS

, 2023
Yana Olehivna Prenko
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Oxygen-rich engineering of lignin-derived porous carbons through potassium activation for zinc ion hybrid capacitors

Resources Chemicals and Materials
Oxygen-rich porous carbons are promising candidates for the carbon-based cathodes of zinc ion hybrid capacitors (ZIHCs). Potassium activation is a traditional and effective way to prepare oxygen-rich porous carbons.
Xueyi Liang, Caiwei Wang, Zicheng Li, Bo Chen, Xuemin Cui, Yuanyuan Ge, Zhili Li   +6 more
doaj   +1 more source