Results 61 to 70 of about 6,996,748 (368)

Adaptive Process Management in Cyber-Physical Domains [PDF]

open access: yes, 2017
The increasing application of process-oriented approaches in new challenging cyber-physical domains beyond business computing (e.g., personalized healthcare, emergency management, factories of the future, home automation, etc.) has led to reconsider the ...
Marrella, Andrea, Mecella, Massimo
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Participatory process management [PDF]

open access: yes, 2008
Although the process of public and stakeholder participation continues to be intensively investigated and discussed in academic circles, the implementation of participatory methods in practice remains problematic.
Hare, M., Krywkow, J.
core   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Model for implementing a reengineering solution of the production process in a printing house

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
The main objective of the present paper is to highlight the importance and impact of the concept of reengineering, both by identifying certain opportunities to improve the performance of Romanian printing companies and some strategies of total redesign ...
Epure Dănuţ-Tiberius   +3 more
doaj   +1 more source

An Industry 4.0: Strategy Direction Of An Airline Operations Performance

open access: yesJurnal Manajemen Indonesia, 2021
Air transport is an industry 4.0 sector of priority that continues to evolve as the era becomes the backbone of a country's economy. The opening of the economic market in all regions of the world has increased the complexity of air transportation ...
Dewi Nusraningrum   +2 more
doaj   +1 more source

Active Anomaly Detection for Key Item Selection in Process Auditing [PDF]

open access: yes, 2022
Process mining allows auditors to retrieve crucial information about transactions by analysing the process data of a client. We propose an approach that supports the identification of unusual or unexpected transactions, also referred to as exceptions ...
Beerepoot, Iris   +10 more
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

open access: yesAging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen   +3 more
wiley   +1 more source

Automation of management processes [PDF]

open access: yesE3S Web of Conferences, 2019
Artificial intelligence and service automation are the key to these kinds of new, product-related services. They increasingly penetrate the traditional mechanical and plant engineering sector and open up potentials for innovative services. Tourism services providers are going through rapid changes and the role of Information and Communication ...
Luis Ochoa Siguencia, Piotr Halemba
openaire   +3 more sources

Home - About - Disclaimer - Privacy