Results 41 to 50 of about 1,354,041 (282)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Assessment of Heavy Metal Soil Contamination and Remediation Strategies in Eastern Slovakia: A Case Study from Dargov

Agriculture
Heavy metal contamination of agricultural soils represents a critical environmental and agronomic challenge, particularly in regions exposed to intensive land use and transport-related emissions.
Ivanna Betušová, Samer Khouri, Marian Šofranko, Andrea Šofranková, Miroslav Betuš   +4 more
doaj   +1 more source

Investigation of the Energy Evolution of Tectonic Coal under Triaxial Cyclic Loading with Different Loading Rates and the Underlying Mechanism

Energies, 2021
It is of great significance to ascertain the mechanical characteristics and deformation laws of tectonic coal that is under complex stress conditions for safe production, but the targeted research in this area is still insufficient at present. This paper
Deyi Gao, Shuxun Sang, Shiqi Liu, Jishi Geng, Tao Wang, Tengmin Sun   +5 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Methods for Rescuing People Using Climbing Equipment in Abandoned Mines to Be Carried Out by Rescue Units of the Integrated Rescue System

Safety
This article discusses the possibilities and methods for rescuing people from abandoned mine workings and the cooperation of the components of the Integrated Rescue System of the Slovak Republic when carrying out rescue work in underground spaces ...
Marek Szücs, Miroslav Betuš, Martin Konček, Marian Šofranko, Andrea Šofranková   +4 more
doaj   +1 more source

The identification of geosites as elements of geotourism offer in Kysuce region, Slovakia

Dela, 2017
The paper analyses the origin and evolution of the Kysuce landscape from the Mesozoic era until the arrival of humans, identifying the relics of these historical evolutionary stages in the present-day landscape. It presents the most important relics from
Pavel Hronček, Pavol Rybár, Ľubomír Štrba, Ladislav Hvizdák, Mário Molokáč, Miloš Jesenský   +5 more
doaj   +1 more source

Corporate Social Responsibility and the Mining Sector in Southern Africa: A Focus on Mining in Malawi, South Africa and Zambia [PDF]

, 2008
The research conducted by the Bench Marks Foundation on mining in Southern provides SADC governments, mining companies and local mining community stakeholders with information and guidance on issues to consider in the process of empowerment and ...

core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Optimizing Emergency Response in Healthcare Facilities: Integration of Firefighting Technologies and Tactical Evacuation Strategies

Fire
This study analyzes the implementation of firefighting procedures and evacuation methods in a hospital environment, with a focus on ensuring rapid rescue operations and evacuation methods in a real fire in 2024.
Miroslav Betuš, Andrea Seňová, Annamária Behúnová, Ivanna Burachok, Galya Toteva Terzieva   +4 more
doaj   +1 more source

CASP-DM: Context Aware Standard Process for Data Mining [PDF]

, 2017
We propose an extension of the Cross Industry Standard Process for Data Mining (CRISPDM) which addresses specific challenges of machine learning and data mining for context and model reuse handling.
Contreras-Ochando, Lidia, Ferri, Cèsar, Flach, Peter, Hernández-Orallo, José, Kull, Meelis, Lachiche, Nicolas, Martínez-Plumed, Fernando, Ramírez-Quintana, María José   +7 more
core   +2 more sources