Results 91 to 100 of about 950,688 (293)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Finding the optimal way to build an information security system based on Markov chains

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The study examined the main aspects of building an information security system from the point of view of optimizing the resources spent and funds to ensure information security. Method.
A. M. Konakov, I. I. Livshits
doaj   +1 more source

Agarose Cryogels: Production Process Modeling and Structural Characterization. [PDF]

open access: yesGels, 2023
Mancino R   +8 more
europepmc   +1 more source

Wastewater Treatment Plant: Modelling and Validation of an Activated Sludge Process [PDF]

open access: gold, 2020
Francesco Calise   +3 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

CREATING A FOUNDATION FOR BUSINESS PROCESS AUTOMATION: A METHODOLOGICAL APPROACH TO STRUCTURING

open access: yesЕкономіка та суспільство
Business process automation requires a thoroughly structured foundation to ensure operational efficiency, accuracy, and long-term adaptability. This article introduces a comprehensive methodology for business process declaration, viewed as an essential ...
Ліана Мазник   +1 more
doaj   +1 more source

Modelling of technological process of joining steel ropes with the use of powder antifriction material and a conductor

open access: diamond, 2021
Edward Marchenko   +4 more
openalex   +1 more source

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