Results 171 to 180 of about 39,470,906 (335)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Movement-level process modeling of microsurgical bimanual and unimanual tasks. [PDF]

open access: yesInt J Comput Assist Radiol Surg, 2022
Koskinen J   +4 more
europepmc   +1 more source

Processed data for "Model identification of neural encoding (MINE)" publication

open access: green, 2023
Kaarthik A Balakrishnan   +3 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Process Modeling and Simulation of Tableting-An Agent-Based Simulation Methodology for Direct Compression. [PDF]

open access: yesPharmaceutics, 2021
Martin NL   +5 more
europepmc   +1 more source

Modelling and analyzing multi-core COTS processors

open access: green, 2022
Frédéric Boniol   +4 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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