Results 91 to 100 of about 4,205,927 (281)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Vision-aided Monitoring and Control of Thermal Spray, Spray Forming, and Welding Processes [PDF]

open access: yes, 1993
Vision is one of the most powerful forms of non-contact sensing for monitoring and control of manufacturing processes. However, processes involving an arc plasma or flame such as welding or thermal spraying pose particularly challenging problems to ...
Agapakis, John E., Bolstad, Jon
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Enantioselective maternal transfer of chiral pesticide metabolite o,p’-DDD in zebrafish (Danio rerio): Implications for intergenerational thyroid disruption

open access: yesEnvironmental Chemistry and Ecotoxicology
Recent studies show that pesticides can induce intergenerational toxicity, posing threats to wildlife populations. However, the intergenerational effects of chiral pesticide metabolites remain understudied despite their known enantioselective ...
Lili Niu   +10 more
doaj   +1 more source

Effect of Bath ZrO2 Concentration on the Properties of Ni-Co/ZrO2 Coatings Obtained by Electrodeposition

open access: yesInternational Journal of Electrochemical Science, 2018
Ni-Co/ZrO2 composite coatings with different ZrO2 contents have been prepared by electrodeposition. The ZrO2 content was controlled by deploying different ZrO2 particle concentrations in the bath. Micrographs, composition, microstructure, micro-hardness,
Sirui Li   +7 more
doaj   +1 more source

Process monitoring IAN Agroparks in India : Transforum report 2009 [PDF]

open access: yes
This is the first report of the TransForum project Process monitoring agroparks international, which focuses on India and specific on the development of the IFFCO Kisan SEZ Nellore in the south of India.
Chakravarthy, G.K.D.K.   +2 more
core   +1 more source

Gear wear process monitoring using acoustic signals [PDF]

open access: yes, 2014
Airborne acoustic signals contain valuable information from machines and can be detected remotely for condition monitoring. However, the signal is often seriously contaminated by various noises from the environment as well as nearby machines.
Ahmaida, Anwar   +3 more
core  

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