Results 101 to 110 of about 4,205,927 (281)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Models for interrupted monitoring of a stochastic process [PDF]

As computers are added to the cockpit, the pilot's job is changing from of manually flying the aircraft, to one of supervising computers which are doing navigation, guidance and energy management calculations as well as automatically flying the aircraft.
Palmer, E.
core   +1 more source

Multivariate statistical process monitoring [PDF]

, 2012
U industrijskoj proizvodnji prisutan je stalni rast zahtjeva, u prvom redu, u pogledu ekonomičnosti proizvodnje, kvalitete proizvoda, stupnja sigurnosti i zaštite okoliša.
Dražen Slišković, Ratko Grbić, Željko Hocenski   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Perinatal exposure to 4-hydroxy-4′-isopropoxydiphenylsulfone alters the adipogenesis in adult mice: A sex-specific study

Ecotoxicology and Environmental Safety
4-hydroxy-4′-isopropoxydiphenylsulfone (BPSIP), a common alternative to bisphenol A (BPA), has been detected in breast milk and across placental barriers. However, the long-term impacts of perinatal exposure to BPSIP on adipogenesis and susceptibility to
Shengnan Zhang, Jiatong Shen, Kaini Hu, Yitong Zhou, Yumeng Wang, Xin Wang, Kashif Hayat, Mingrong Qian   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Polycyclic aromatic hydrocarbons in paddy soils: Distribution, source apportionment, and risk assessment in major rice-growing regions of China

Environmental Chemistry and Ecotoxicology
Polycyclic aromatic hydrocarbons (PAHs) in agricultural environments and their potential health impacts have raised significant concern, particularly due to their substantial emissions from biomass and coal combustion. However, the environmental fate and
Daoyu Liu, Lili Niu, Zili Guo, Shuduan Mao, Shuren Liu, Dongmei Xu, Chao Xu, Xiaohui Sun, Haiying Yu, Weiping Liu   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Towards an ontology for process monitoring and mining [PDF]

, 2007
Business Process Analysis (BPA) aims at monitoring, diagnosing, simulating and mining enacted processes in order to support the analysis and enhancement of process models.
Domingue, John, Pedrinaci, Carlos
core   +2 more sources