Results 141 to 150 of about 14,530,589 (306)
The growth of the modern information technology sector and the safe use of electrical equipment depend on accurate lightning localization monitoring.
Yiming Han, Hongchun Shu, Bin He
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Census Monitoring Board Presidential Members
U.S. Census Monitoring Board is a bipartisan board charged with monitoring the Bureau of the Census' preparations for the 2000 Census and reporting its findings to Congress and the ...
U.S. Census Monitoring Board Presidential Members
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Advances in structural analysis and process monitoring of thermoplastic composite pipes. [PDF]
Okolie O +5 more
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Agent based modeling and monitoring for production process of enterprise
This paper presents a multi-agent production process monitoring and management prototype system of process enterprise, describes system components and functions, web-based multi-agent system framework, global facilitator, the agent representation, agent ...
Zhang SJ(张士杰)
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A Weibull process monitoring with AEWMA control chart: an application to breaking strength of the fibrous composite. [PDF]
Sarwar MA +5 more
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source

