Results 131 to 140 of about 12,132,166 (305)

Porcine Endogenous Retrovirus Risks and Ethical Reconstruction of Xenotransplantation

open access: yesYixue yu zhexue
Pigs are considered excellent donors for xenotransplantation, but porcine endogenous retrovirus (PERV) constitutes a fundamental uncertainty due to its endogenous nature, recombination potential, and unpredictable interactions with the human immune ...
Hongyu CHEN, Song LI
doaj   +1 more source

Data‐Driven and Physics‐Informed Modeling Perspectives for Soft Manipulators: From SINDy to Hybrid Intelligence

open access: yesAdvanced Science, EarlyView.
This Perspective charts the modeling landscape for soft manipulators, spanning sparse system identification, neural dynamics, physics‐informed models and hybrid intelligence. We examine how physics, data, sensing, adaptation and control can assume complementary roles within this landscape, and provide a framework for selecting modeling approaches ...
Wenbo Hui   +4 more
wiley   +1 more source

Lewis Acid‐Catalyzed Strain‐Enabled (3+3) Annulation of Bicyclo[1.1.0]Butanes With Indolylalcohols: Synthesis of Indole‐Fused Aza‐Bicyclo[3.1.1]Heptanes

open access: yesAdvanced Science, EarlyView.
Bicyclo[1.1.0]butanes undergo a Lewis acid‐catalyzed formal (3 + 3) annulation with indolyl alcohols to furnish indole‐fused aza‐bicyclo[3.1.1]heptanes. Strain‐release‐driven C‐C bond formation, followed by C‐N bond formation via ring expansion, enables the rapid assembly of rigid, sp3‐rich bicyclic architectures under mild reaction conditions ...
Mainak Dey   +4 more
wiley   +1 more source

In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He   +20 more
wiley   +1 more source

A. N. Whitehead o vzdelávaní a náboženstve (A. N. Whitehead on Education and Religion)

open access: yesOstium, 2019
The philosophy of education and the philosophy of religion are two different intellectual fields that are not often thought of as intimately connected. However in the process philosophy of A. N. Whitehead they are closely related to each other.
Štefan Zolcer
doaj  

The Coloniality of Western Philosophy: Chinese Philosophy as viewed in France [PDF]

open access: yes, 2013
Chinese philosophy is little known in France and is notgenerally recognised by twenty-first century French philosophers as a philosophy. They often regard its contributions as wisdom, thought or spirituality.
Maitre, Marie-Julie
core  

XChrom: A Cross‐Cell Chromatin Accessibility Prediction Model Integrating Genomic Sequence and Cellular Context

open access: yesAdvanced Science, EarlyView.
XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao   +5 more
wiley   +1 more source

Process categories: the metaphysics, methodology & mathematics, philosophy of nature and process philosophy

open access: yes, 2009
To apply the metaphysical methodology of mathematics to the logic and form of process in natural philosophy requires a metaphysics above modelling, a methodology more than method and a mathematics beyond the set based topics of arithmetic, algebra, geometry and topology.
Heather, Michael, Rossiter, Nick
openaire  

A Course on Economic Justice: The intersection of philosophy and economics [PDF]

open access: yes
The process of teaching a topic that inhabits the upper reaches of both philosophy and economic theory, while swooping as near the earth as political policy, is both exhilarating and terrifying. To do it well is indeed rare. We present our approach, some
Barbour, James L., Batchelor, Nim T.
core  

2007 - 2008 Philosophy Colloquium Series [PDF]

open access: yes, 2007
Series of public talks will provide the opportunity for students, faculty, and community members both within and beyond the Department of Philosophy to hear and discuss stimulating lectures on a wide range of topics that are relevant both to the core ...
Department of Philosophy
core  

Home - About - Disclaimer - Privacy