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Filozofija i Društvo, 2023 This article deals with the problem of cessation in Whitehead’s philosophy. By focusing on his Process and Reality, but also on his other works, different temporal, mereological and other aspects of perishing are analyzed, with special attention
Losoncz Mark
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Genome-wide screening reveals producer-cell modifications that improve virus-like particle production and delivery potency [PDF]
Nature CommunicationsEngineered virus-like particles (eVLPs) are promising vehicles for transient delivery of gene editing agents. While extensive particle engineering has yielded efficient eVLPs, it remains underexplored whether engineering the cells used to produce eVLPs ...
Diana Ly +4 more
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BMC Biology, 2022 Background The mammalian X and Y chromosomes originated from a pair of ordinary autosomes. Over the past ~180 million years, the X and Y have become highly differentiated and now only recombine with each other within a short pseudoautosomal region. While
Jennifer F. Hughes +7 more
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G3: Genes, Genomes, Genetics, 2021 Gene conversion is GC-biased across a wide range of taxa. Large palindromes on mammalian sex chromosomes undergo frequent gene conversion that maintains arm-to-arm sequence identity greater than 99%, which may increase their susceptibility to the effects
Emily K Jackson +3 more
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Nature Communications, 2022 The authors find that the insulin receptor forms dynamic clusters during insulin signaling and that these clusters become dysfunctional in insulin resistance. This dysfunction is partially rescued by metformin, a drug used to treat type 2 diabetes.
Alessandra Dall’Agnese +19 more
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Quantitative Analysis of Cellular Diacylglycerol Content
Bio-Protocol, 2014 Diacylglycerol (DAG) is a bioactive lipid with diverse biological roles. DAG transiently accumulates in a membrane upon receipt of an appropriate stimulus that activates phospholipase C to cleave phospholipids.
Fikadu Tafesse +2 more
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Estudios Latinoamericanos, 2022 El ensayo argumentativo que se presenta tiene dos fines. Evaluar la suficiencia y compleción de una investigación en administración de operaciones dentro de la epistemología de una escuela de humanismo administrativo, y buscar posibles perspectivas ...
Camilo Osejo-Bucheli
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Examining and Comparing the Concept of Experience According to Hegel and Whitehead [PDF]
Journal of Philosophical InvestigationsThe discussion of experience by Hegel and Whitehead is based on a basic and similar basis, but it develops in two completely different directions. The basis of these two philosophers is about the experience of tying the discussion from it to what is ...
Mokhtar Momeni
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Fate specification is spatially intermingled across planarian stem cells
Nature Communications, 2023 Regeneration requires mechanisms for producing a wide array of cell types. Neoblasts are stem cells in the planarian Schmidtea mediterranea that undergo fate specification to produce over 125 adult cell types.
Chanyoung Park +3 more
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Nature Communications, 2020 Halogenated plant natural products are rare and plant halogenation enzymes are thus far unknown. Here Kim et al. identify a dechloroacutumine halogenase from Common Moonseed that catalyzes the final chlorination step in the biosynthesis of acutumine, a ...
Colin Y. Kim +5 more
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