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Analysis and Examination of the Influence of Whitehead's Process Philosophy on Theological Transformation, Focusing on the Issue of "Becoming" [PDF]

Journal of Philosophical Investigations
Alfred North Whitehead's "process philosophy," a novel and influential perspective in contemporary philosophy, examines the organic and interconnected relationships between the various elements of existence and processes.
Mahdi Monazzah, Mohammad Mahdavi, Mohammad Azimi   +2 more
doaj   +1 more source

Emergence of a proton exchange-based isomerization and lactonization mechanism in the plant coumarin synthase COSY

Nature Communications, 2023
Plant biosynthetic enzymes rapidly evolve to catalyze specialized reactions. Here, the authors present the crystal structure and mechanism of COSY, the enzyme involved in coumarin biosynthesis of the BAHD-acyltransferase family that catalyzes an ...
Colin Y. Kim, Andrew J. Mitchell, David W. Kastner, Claire E. Albright, Michael A. Gutierrez, Christopher M. Glinkerman, Heather J. Kulik, Jing-Ke Weng   +7 more
doaj   +1 more source

Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition

Cell Reports, 2020
Summary: The heat shock protein 90 (Hsp90) chaperone functions as a protein-folding buffer and plays a role promoting the evolution of new heritable traits.
Peter Tsvetkov, Timothy J. Eisen, Sven U. Heinrich, Zarina Brune, Erinc Hallacli, Greg A. Newby, Can Kayatekin, David Pincus, Susan Lindquist   +8 more
doaj   +1 more source

Spinal Involvement in Charge Syndrome: Implications for Management

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT CHARGE syndrome (OMIM #214800) is an autosomal dominant disorder caused by mutations in the CHD7 gene in most cases. Although originally defined by the CHARGE acronym (coloboma, heart defects, choanal atresia, growth restriction, genital hypoplasia, and ear anomalies), the recognized phenotype has expanded considerably to include highly ...
Adriana Gomes, Álvaro Martín‐Rodríguez, Miguel del Campo Casanelles, Marilyn C. Jones, Daniela Carvalho, Lynne M. Bird   +5 more
wiley   +1 more source

Investigation of Stray‐Light Patterns in the eROSITA X‐Ray Cameras

Astronomische Nachrichten, EarlyView.
ABSTRACT eROSITA (extended ROentgen Survey with an Imaging Telescope Array) is the soft X‐ray instrument aboard the Spectrum‐Roentgen‐Gamma (SRG) mission, developed under the responsibility of the Max Planck Institute for Extraterrestrial Physics (MPE).
Veronika Stieglitz, Peter Friedrich, Susanne Friedrich, Konrad Dennerl, Michael Freyberg   +4 more
wiley   +1 more source

Firms' Green Responses to Environmental Regulations: A Three‐Dimensional Concurrent Engineering Perspective

Business Strategy and the Environment, EarlyView.
ABSTRACT This study investigates companies' responses to energy efficiency policies, focusing on mandatory and voluntary regulations that create a complex landscape for businesses to navigate. Using a sample of 1473 firms across 29 European countries (2002–2018), we explore the impact of legislation on green redesign—operationalized through ...
Thomas Alexopoulos, Dimitra Kalaitzi, Giorgos Papagiannakis, Konstantina Spanaki   +3 more
wiley   +1 more source

5′ UTR length shapes alternative N-terminal protein isoforms across cancers and in rare disease

EMBO Reports
The 5′ untranslated region (5′ UTR) of an mRNA is classically viewed as a regulatory region that controls the amount of protein production, but not the resulting protein sequence. Here, we demonstrate that 5′ UTR length plays a direct role in alternative
Jimmy Ly, Eric M Smith, Matteo Di Bernardo, Yi Fei Tao, Elizabeth M Black, Ekaterina Khalizeva, Iain M Cheeseman   +6 more
doaj   +1 more source

Beyond Structural Interventions: The Human Architecture Shaping ESG Integration in Corporate Systems

Business Strategy and the Environment, EarlyView.
ABSTRACT Despite the promotion of ESG in corporate discourse, substantive integration of ESG principles into business practices remains challenging. This study applies and extends Meadows' leverage framework to examine ESG integration in UAE‐listed firms.
M. Schulte, Dimitris Christopoulos
wiley   +1 more source

Global stabilization of the transcriptome in mitotic cells

The EMBO Journal
In the presence of cell division errors, mammalian cells can pause in mitosis for tens of hours with little to no transcription, while still requiring continued translation for viability. These unique aspects of mitosis require substantial adaptations to
Ekaterina Khalizeva, Arash Latifkar, Kehui Xiang, David P Bartel, Jimmy Ly, Iain M Cheeseman   +5 more
doaj   +1 more source

Czas ciągły i dyskretny a istnienie zawisłe i niezawisłe

Studia Philosophica Wratislaviensia
This article serves as a polemical gloss to Marek Rosiak’s paper ‟Metafizyka genezy: Arystoteles i Whitehead”. The primary dispute concerns Alfred North Whitehead’s postulation of discrete time, which the author argues is an a priori metaphysical ...
Marcin Jancewicz
doaj   +1 more source