Results 21 to 30 of about 363,740 (285)
New CRISPR Mutagenesis Strategies Reveal Variation in Repair Mechanisms among Fungi
We have created new vectors for clustered regularly interspaced short palindromic repeat (CRISPR) mutagenesis in Candida albicans, Saccharomyces cerevisiae, Candida glabrata, and Naumovozyma castellii.
Valmik K. Vyas +7 more
doaj +1 more source
Power, Possibility, and Agency: Speculative Realism and Whitehead’s Theory of Relations
At the turn of the twentieth century, the debate between supporters of internal and external relations showed how our assumptions on the nature of relations result in ontological, epistemic, and ethical commitments. In this debate, Alfred North Whitehead
Christian Frigerio
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On the Generating Hypothesis in Noncommutative Stable Homotopy [PDF]
Freyd's Generating Hypothesis is an important problem in topology with deep structural consequences for finite stable homotopy. Due to its complexity some recent work has examined analogous questions in various other triangulated categories.
Mahanta, Snigdhayan
core +1 more source
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1
PERK stress signaling is an important driver of cancer invasion and metastasis, but chemical inhibitors of PERK cause side effects. Here, the authors find that CREB3L1 is required for PERK's pro-metastatic function in breast cancer, and its inhibition ...
Yu-Xiong Feng +5 more
doaj +1 more source
Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition
Summary: The heat shock protein 90 (Hsp90) chaperone functions as a protein-folding buffer and plays a role promoting the evolution of new heritable traits.
Peter Tsvetkov +8 more
doaj +1 more source
Proof of the volume conjecture for Whitehead doubles of a family of torus knots
A technique to calculate the colored Jones polynomials of satellite knots, illustrated by the Whitehead doubles of knots, is presented. Then we prove the volume conjecture for Whitehead doubles of a family of torus knots and show some interesting ...
Hao Zheng +7 more
core +3 more sources
Fertility across metazoa requires the germline-specific DAZ family of RNA-binding proteins. Here we examine whether DAZL directly regulates progenitor spermatogonia using a conditional genetic mouse model and in vivo biochemical approaches combined with ...
Maria M Mikedis +7 more
doaj +1 more source
Knot Floer homology of Whitehead doubles
In this paper we study the knot Floer homology invariants of the twisted and untwisted Whitehead doubles of an arbitrary knot K. We present a formula for the filtered chain homotopy type of HFK(D(+,K,t)) in terms of the invariants for K, where D(+,K,t ...
Akbulut +9 more
core +2 more sources
¿Existen las máquinas vivientes? Sobre la relación entre vida y técnica
La biotecnología industrial llama a los productos de la biología sintética “living machines”. Como quiero demostrar en este artículo, la noción de una “máquina viviente” es engañosa.
Stascha Rohmer
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A Rhythmic Process of Harmonization: Whitehead’s Concept of Aesthetic Experience
Book review of Dadejík, O., Kaplický, M., Ševčík, M., and Zuska, V. (2021) Process and Aesthetics: An Outline of Whiteheadian Aesthetics and Beyond. Prague: Karolinum Press. ISBN 978-80-246-4726-5.
Botond Csuka
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