Results 21 to 30 of about 102,007 (301)
m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis
Nature Communications, 2019 Ime4p is a yeast N6-methyladenosine (m6A) methyltransferase with an unknown role in meiosis. Rme1p is a repressor of meiosis. Here the authors show that Ime4p methylates RME1 3′ UTR to reduce its expression and enable meiosis, thus providing an example ...
G. Guy Bushkin +7 more
doaj +1 more source
Examining and Comparing the Concept of Experience According to Hegel and Whitehead [PDF]
Journal of Philosophical InvestigationsThe discussion of experience by Hegel and Whitehead is based on a basic and similar basis, but it develops in two completely different directions. The basis of these two philosophers is about the experience of tying the discussion from it to what is ...
Mokhtar Momeni
doaj +1 more source
Power, Possibility, and Agency: Speculative Realism and Whitehead’s Theory of Relations
Eidos. A Journal for Philosophy of Culture, 2020 At the turn of the twentieth century, the debate between supporters of internal and external relations showed how our assumptions on the nature of relations result in ontological, epistemic, and ethical commitments. In this debate, Alfred North Whitehead
Christian Frigerio
doaj +1 more source
Liver Transplantation, EarlyView., 2022 Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala +6 more
wiley +1 more source
Dynamic changes in ORC localization and replication fork progression during tissue differentiation
BMC Genomics, 2018 Background Genomic regions repressed for DNA replication, resulting in either delayed replication in S phase or underreplication in polyploid cells, are thought to be controlled by inhibition of replication origin activation.
Brian L. Hua +4 more
doaj +1 more source
Fate specification is spatially intermingled across planarian stem cells
Nature Communications, 2023 Regeneration requires mechanisms for producing a wide array of cell types. Neoblasts are stem cells in the planarian Schmidtea mediterranea that undergo fate specification to produce over 125 adult cell types.
Chanyoung Park +3 more
doaj +1 more source
International review of planning Systems, Christine Whitehead
, 2017 On 10 May 2017, Christine Whitehead presented at the Department for Communities and Local Government (DCLG) planners away day. Her presentation, ‘International Review of Planning Systems‘, provided just that, a review of international planning systems ...
Whitehead, Christine
core +5 more sources
New CRISPR Mutagenesis Strategies Reveal Variation in Repair Mechanisms among Fungi
mSphere, 2018 We have created new vectors for clustered regularly interspaced short palindromic repeat (CRISPR) mutagenesis in Candida albicans, Saccharomyces cerevisiae, Candida glabrata, and Naumovozyma castellii.
Valmik K. Vyas +7 more
doaj +1 more source
SYK kinase mediates brown fat differentiation and activation
Nature Communications, 2017 Spleen protein tyrosine kinase (Syk) has so far been mainly studied in haematopoietic and immune cells. Here, the authors show that Syk also has a role in brown adipose tissue, where it regulates the formation of brown adipocytes and their thermogenic ...
Marko Knoll +11 more
doaj +1 more source
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1
Nature Communications, 2017 PERK stress signaling is an important driver of cancer invasion and metastasis, but chemical inhibitors of PERK cause side effects. Here, the authors find that CREB3L1 is required for PERK's pro-metastatic function in breast cancer, and its inhibition ...
Yu-Xiong Feng +5 more
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