Results 11 to 20 of about 77,413 (314)
Halogenated plant natural products are rare and plant halogenation enzymes are thus far unknown. Here Kim et al. identify a dechloroacutumine halogenase from Common Moonseed that catalyzes the final chlorination step in the biosynthesis of acutumine, a ...
Colin Y. Kim +5 more
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On Whitehead’s algorithm [PDF]
Using graph theoretic techniques the author generalizes a theorem of Whitehead and a theorem of McCool. More precisely he announces the following. ''One can decide effectively when two finitely generated subgroups of a finitely generated free group F are equivalent under an automorphism of F.
openaire +3 more sources
El ensayo argumentativo que se presenta tiene dos fines. Evaluar la suficiencia y compleción de una investigación en administración de operaciones dentro de la epistemología de una escuela de humanismo administrativo, y buscar posibles perspectivas ...
Camilo Osejo-Bucheli
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Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala +6 more
wiley +1 more source
m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis
Ime4p is a yeast N6-methyladenosine (m6A) methyltransferase with an unknown role in meiosis. Rme1p is a repressor of meiosis. Here the authors show that Ime4p methylates RME1 3′ UTR to reduce its expression and enable meiosis, thus providing an example ...
G. Guy Bushkin +7 more
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Dynamic changes in ORC localization and replication fork progression during tissue differentiation
Background Genomic regions repressed for DNA replication, resulting in either delayed replication in S phase or underreplication in polyploid cells, are thought to be controlled by inhibition of replication origin activation.
Brian L. Hua +4 more
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Plant biosynthetic enzymes rapidly evolve to catalyze specialized reactions. Here, the authors present the crystal structure and mechanism of COSY, the enzyme involved in coumarin biosynthesis of the BAHD-acyltransferase family that catalyzes an ...
Colin Y. Kim +7 more
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SYK kinase mediates brown fat differentiation and activation
Spleen protein tyrosine kinase (Syk) has so far been mainly studied in haematopoietic and immune cells. Here, the authors show that Syk also has a role in brown adipose tissue, where it regulates the formation of brown adipocytes and their thermogenic ...
Marko Knoll +11 more
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New CRISPR Mutagenesis Strategies Reveal Variation in Repair Mechanisms among Fungi
We have created new vectors for clustered regularly interspaced short palindromic repeat (CRISPR) mutagenesis in Candida albicans, Saccharomyces cerevisiae, Candida glabrata, and Naumovozyma castellii.
Valmik K. Vyas +7 more
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Power, Possibility, and Agency: Speculative Realism and Whitehead’s Theory of Relations
At the turn of the twentieth century, the debate between supporters of internal and external relations showed how our assumptions on the nature of relations result in ontological, epistemic, and ethical commitments. In this debate, Alfred North Whitehead
Christian Frigerio
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