Results 51 to 60 of about 363,740 (285)

A Systematic Review and Meta‐Analysis of Cardiac Interoceptive Accuracy in Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Interoceptive impairments have been suggested as an etiological factor in anorexia nervosa (AN) but have not been consistently confirmed across interoceptive dimensions and bodily systems. This systematic review and meta‐analysis provides a focused investigation of cardiac interoceptive accuracy (IAcc) in AN.
Claire Gend, Laure Remy, Annika P. C. Lutz   +2 more
wiley   +1 more source

Widespread Changes in the Posttranscriptional Landscape at the Drosophila Oocyte-to-Embryo Transition

Cell Reports, 2014
The oocyte-to-embryo transition marks the onset of development. The initial phase of this profound change from the differentiated oocyte to the totipotent embryo occurs in the absence of both transcription and mRNA degradation.
Iva Kronja, Bingbing Yuan, Stephen W. Eichhorn, Kristina Dzeyk, Jeroen Krijgsveld, David P. Bartel, Terry L. Orr-Weaver   +6 more
doaj   +1 more source

Higher Whitehead torsion and the geometric assembly map

, 2012
We construct a higher Whitehead torsion map, using algebraic K-theory of spaces, and show that it satisfies the usual properties of the classical Whitehead torsion.
Steimle, Wolfgang
core   +1 more source

Recommendations for structural magnetic resonance imaging in infants with first afebrile seizure or new onset epilepsy: Evidence‐based recommendations from the ILAE Neuroimaging Task Force

Epilepsia, EarlyView.
Abstract Infants aged 1–24 months with new onset epilepsy frequently present with structural brain abnormalities, yet no updated evidence‐based magnetic resonance imaging (MRI) guidelines exist for this population. The International League Against Epilepsy (ILAE) Neuroimaging Task Force developed evidence‐based recommendations for structural brain MRI ...
Gavin P. Winston, Simone Salemme, Gaetano Cantalupo, Fernando Cendes, Felice D′Arco, Paolo Federico, William D. Gaillard, Eliane Kobayashi, Edward J. Novotny, Godwin Ogbole, Abdul Kareem Pullattayil, Domenico Tortora, Matthew T. Whitehead, Taoyun Yi, Francesco Brigo, Anna Elisabetta Vaudano   +15 more
wiley   +1 more source

Genetically encoded fluorescent reporter for polyamines

Nature Communications
Polyamines are abundant and evolutionarily conserved metabolites that are essential for life. Dietary polyamine supplementation extends life-span and health-span. Dysregulation of polyamine homeostasis is linked to Parkinson’s disease and cancer, driving
Pushkal Sharma, Colin Y. Kim, Heather R. Keys, Shinya Imada, Alex B. Joseph, Luke Ferro, Tenzin Kunchok, Rachel Anderson, Yulin Sun, Ömer H. Yilmaz, Jing-Ke Weng, Ankur Jain   +11 more
doaj   +1 more source

MicroRNA-125b transforms myeloid cell lines by repressing multiple mRNA

Haematologica, 2012
Background We previously described a t(2;11)(p21;q23) chromosomal translocation found in patients with myelodysplasia or acute myeloid leukemia that leads to over-expression of the microRNA miR-125b, and we showed that transplantation of mice with murine
Marina Bousquet, Diu Nguyen, Cynthia Chen, Lauren Shields, Harvey F. Lodish   +4 more
doaj   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

Goodwillie calculus and Whitehead products

, 2011
We prove that iterated Whitehead products of length (n+1) vanish in any value of an n-excisive functor in the sense of Goodwillie. We compare then different notions of homotopy nilpotency, from the Berstein-Ganea definition to the Biedermann-Dwyer one ...
Chorny, Boris, Scherer, Jerome
core   +1 more source

First Report of Homozygous COL7A1 c.5756delG Mutation Causing Recessive Dystrophic Epidermolysis Bullosa in a Non‐Consanguineous Japanese Family

JEADV Clinical Practice, EarlyView.
ABSTRACT Severe recessive dystrophic epidermolysis bullosa (RDEB) is usually caused by biallelic loss‐of‐function mutations in COL7A1. While the c.5756delG variant has been previously reported in heterozygous form, its clinical impact in homozygosity has not been described.
Nozomi Kohama, Sayaka Yamaguchi, Teruki Yanagi, Yumi Akamine, Kimiko Nonaka, Daisuke Utsumi, Kenzo Takahashi   +6 more
wiley   +1 more source

A statistical approach for identifying primary substrates of ZSWIM8-mediated microRNA degradation in small-RNA sequencing data

BMC Bioinformatics, 2023
Background One strategy for identifying targets of a regulatory factor is to perturb the factor and use high-throughput RNA sequencing to examine the consequences.
Peter Y. Wang, David P. Bartel
doaj   +1 more source