Results 101 to 110 of about 15,701,455 (293)

Risk Performance Analysis on Navigation of MASS via a Hybrid Framework of STPA and HMM: Evidence from the Human–Machine Co-Driving Mode

open access: yesJournal of Marine Science and Engineering
The remote control ship is considered to be the most likely implementation of maritime autonomous surface ships (MASS) in the near-term future. With collaborative control from onboard controllers and operators ashore, ships may operate in three ...
Wei Li   +5 more
doaj   +1 more source

Investigation into the Potential Migration of Nanoparticles from Laponite-Polymer Nanocomposites

open access: yesNanomaterials, 2018
In this study, the migration potential of laponite, a small synthetic nanoclay, from nanocomposites into foods was investigated. First, a laponite/ethylene vinyl acetate (EVA) masterbatch was compounded several times and then extruded into thin low ...
Johannes Bott, Roland Franz
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Evaluating the Status of Process Safety Management in Process Industries: A Systematic Review

open access: yesبهداشت و ایمنی کار
Introduction: For years, chemical process industries have reported the unexpected release of highly hazardous liquids and gases. A disaster could not be avoided when these materials were not adequately controlled.
Elahe Chubineh   +3 more
doaj  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Special issue: Process safety in times of a pandemic. [PDF]

open access: yesJ Loss Prev Process Ind, 2022
Cozzani V, Yang M.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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