Results 1 to 10 of about 2,328,331 (167)
Journal of Nanobiotechnology, 2021 Bacterial biofilm is the complicated clinical issues, which usually results in bacterial resistance and reduce the therapeutic efficacy of antibiotics.
Xiangjun Chen +6 more
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Journal of Nanobiotechnology, 2021 Background Biofilm formation is one of the main reasons for persistent bacterial infections. Recently, pH-sensitive copolymers have fascinated incredible attention to tackle biofilm-related infections.
Rong Guo +7 more
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Molecules, 2023 In this study, a collection of newly developed α-methylchalcone derivatives were synthesized and assessed for their inhibitory potential against human cervical cancer cell lines (HeLa, SiHa, and C33A) as well as normal human cervical epithelial cells (H8)
Zheng Yang +5 more
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Clinical Chemistry and Laboratory Medicine, 1987 Enzyme release was studied in various tissues in intact animals or by means of tissue slices, organ perfusion or isolated and cultured cells. The factors that determine the extent and the time course of the leakage were studied extensively with several liver enzymes.
Schmidt, Ellen, Schmidt, F. W.
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Modular assembly of indole alkaloids enabled by multicomponent reaction
Nature Communications, 2023 Indole alkaloids are one of the largest alkaloid classes, proving valuable structural moiety in pharmaceuticals. Although methods for the synthesis of indole alkaloids are constantly explored, the direct single-step synthesis of these chemical entities ...
Jiaming Li +4 more
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A fluorescence sensor for nitroreductase detection in hypoxic cells and zebrafish
Results in Chemistry, 2021 Nitroreductase (NTR) is a type of cytoplasmic enzyme that depends on flavin mononucleotide or flavin adenine dinucleotide, and that is widely present in tumor cells where it increases during hypoxia. NTR can effectively reduce aromatic nitro compounds to
Wan Sun +7 more
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Nano Composite Fe-Co-V /Zeolite as a Nano Carrier for Folic Acid Drug Controlled Release [PDF]
Trends in Pharmaceutical Sciences, 2021 large reserves of zeolites has been one of the comparative advantages of the country in this field and provides economic justification for its use in a variety of applications, including medical and pharmaceutical fields such as artificial kidney ...
Shima Zangeneh Yousef Abadi +2 more
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Hydrogel-Based Microneedle as a Drug Delivery System
Pharmaceutics, 2023 The skin is considered the largest and most accessible organ in the human body, and allows the use of noninvasive and efficient strategies for drug administration, such as the transdermal drug delivery system (TDDS).
David Filho +4 more
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Nature Reviews Neuroscience, 2013 The encoding of salient events as memory traces involves the selective activation of specific neurons in the hippocampus and the inhibition of others, a process shown here to be regulated by GABAergic input from the nucleus incertus in the brainstem.
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Frontiers in Bioinformatics, 2021 Ten years ago, the dramatic rise in the number of microbial genomes led to an inflection point, when the approach of finding short, exact matches in a comprehensive database became just as accurate as older, slower approaches. The new idea led to a method that was hundreds of times times faster than those that came before.
Steven L. Salzberg +5 more
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