Results 1 to 10 of about 1,668,634 (294)

Strategies for sensing neurotransmitters with responsive MRI contrast agents

open access: yesChemical Society Reviews, 2017
This review introduces current and potential chemistry approaches in molecular fMRI that allow direct imaging of neurotransmitters.
Angelovski, Goran, Tóth, Éva
openaire   +6 more sources

Disminución del número de neuronas que expresan GABA en la corteza cerebral de ratones infectados con rabia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Algunos signos clínicos de la rabia y estudios experimentales previos sugieren que esta infección viral podría afectar al sistema GABAérgico. Objetivo. Evaluar el efecto de la infección con el virus de la rabia sobre la expresión de GABA en
Aura Caterine Rengifo   +1 more
doaj   +1 more source

Cognitive Decline in Neuronal Aging and Alzheimer's Disease: Role of NMDA Receptors and Associated Proteins

open access: yesFrontiers in Neuroscience, 2017
Molecular changes associated with neuronal aging lead to a decrease in cognitive capacity. Here we discuss these alterations at the level of brain regions, brain cells, and brain membrane and cytoskeletal proteins with an special focus in NMDA molecular ...
Jesús Avila   +13 more
doaj   +1 more source

THE EFFECT OF THE CONVULSANT AGENT, CATECHOL, ON NEUROTRANSMITTER UPTAKE AND RELEASE IN RAT BRAIN SLICES [PDF]

open access: yesBritish Journal of Pharmacology, 1981
The effect of catechol on uptake and K+‐stimulated release of γ‐aminobutyric acid (GABA), D‐aspartate, noradrenaline and acetylcholine has been studied in slices of cerebral cortex and thalamus. Low concentrations of catechol did not influence the uptake of any of the neurotransmitters in either brain area.
M C, Minchin, G, Pearson
openaire   +2 more sources

Robot technology identifies a Parkinsonian therapeutics repurpose to target stem cells of glioblastoma

open access: yesCNS Oncology, 2020
Aim: Glioblastoma is a heterogeneous lethal disease, regulated by a stem-cell hierarchy and the neurotransmitter microenvironment. The identification of chemotherapies targeting individual cancer stem cells is a clinical need.
Andres Vargas-Toscano   +10 more
doaj   +1 more source

Blood platelet research in autism spectrum disorders: In search of biomarkers

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2019
Autism spectrum disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder that is caused by gene‐environment interactions. To improve its diagnosis and treatment, numerous efforts have been undertaken to identify reliable biomarkers for ...
Manisha Padmakumar   +3 more
doaj   +1 more source

Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells

open access: yesmSphere, 2021
Coxiella burnetii causes the debilitating disease Q fever in humans. This infection is difficult to treat with current antibiotics and can progress to long-term, potentially fatal infection in immunocompromised individuals or when treatment is delayed.
Marissa S. Fullerton   +5 more
openaire   +3 more sources

Neurochemical Modulating Effect of Boswellia serrata Roxb. ex Colebr: A Preclinical Research

open access: yesPharmaceutical and Biomedical Research, 2022
Background: Boswellia serrata has been known for many decades and mentioned in the ancient Ayurvedic texts. Many previous studies have demonstrated its role in depression and anxiety in animal models.
Prabhakar Adake   +2 more
doaj  

Elucidating the Role of Neurotensin in the Pathophysiology and Management of Major Mental Disorders

open access: yesBehavioral Sciences, 2014
Neurotensin (NT) is a neuropeptide that is closely associated with, and is thought to modulate, dopaminergic and other neurotransmitter systems involved in the pathophysiology of various mental disorders.
Mona M Boules   +3 more
doaj   +1 more source

The Relationship Between Dopamine Neurotransmitter Dynamics and the Blood-Oxygen-Level-Dependent (BOLD) Signal: A Review of Pharmacological Functional Magnetic Resonance Imaging

open access: yesFrontiers in Neuroscience, 2018
Functional magnetic resonance imaging (fMRI) is widely used in investigations of normal cognition and brain disease and in various clinical applications. Pharmacological fMRI (pharma-fMRI) is a relatively new application, which is being used to elucidate
Tyler J. Bruinsma   +14 more
doaj   +1 more source

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