Results 41 to 50 of about 14,034,560 (296)

Functional Coupling Degree and Human Activity Intensity of Production–Living–Ecological Space in Underdeveloped Regions in China: Case Study of Guizhou Province

open access: yesLand, 2021
(1) Background: Clarify the coordinated development level of production, living, and ecological spaces in the underdeveloped areas of China and their relationship with the intensity of human activity.
Xuesong Zhang, Zijin Xu
doaj   +1 more source

Reuse in software process simulation modeling

open access: yes, 2022
4 S. : Lit.Many simulation models of software development processes were created in the recent years and a lot of effort was spent during the development of detailed models.
Rus, I., Neu, H.
core  

Spatial-Temporal Evolution of Agricultural Carbon Balance at Township Scale and Carbon Compensation Zoning: A Case Study of Guangshui City, Hubei Province

open access: yesLand
Optimizing agricultural carbon compensation zoning is crucial for establishing robust mechanisms in agricultural carbon compensation management, with significant implications for achieving national “dual carbon” strategic objectives. This study employs K-
Zhengkun Yang   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Criteria for the evaluation of business process simulation tools [PDF]

open access: yes, 2007
This paper focuses on a process of simulation software packages selection in the context of business process change projects. The paper presents discrete event simulation, its relation to business process modelling and examples of its practical ...
Bosilj-Vuksic, V., Hlupic, V., Ceric, V.
core  

Special Issue on “Process Modelling and Simulation”

open access: yes, 2019
Collecting and highlighting novel developments that address existing as well as forthcoming challenges in the field of process modelling and simulation was the motivation for proposing this special issue on “Process Modelling and Simulation&rdquo ...
Constantinos C. Pantelides   +2 more
core   +1 more source

Vulnerability Assessment of Soil Erosion in Southwestern Hubei Province Based on RUSLE Model and Geographic Detector

open access: yesShuitu Baochi Xuebao
[Objective] Soil erosion is a prominent ecological problem in southwestern Hubei Province. A reasonable assessment of the vulnerability of soil erosion in this area and exploration of its driving mechanisms are prerequisites for effective soil and water ...
YANG Yanpan   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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