Results 61 to 70 of about 3,003,956 (306)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Simulation of Stimuli-Responsive Polymer Networks
Chemosensors, 2013 The structure and material properties of polymer networks can depend sensitively on changes in the environment. There is a great deal of progress in the development of stimuli-responsive hydrogels for applications like sensors, self-repairing materials ...
Thomas Gruhn, Heike Emmerich
doaj +1 more source
An Evaluation Model of Level of Detail Consistency of Geographical Features on Digital Maps
ISPRS International Journal of Geo-Information, 2020 This paper proposes a method to evaluate the level of detail (LoD) of geographic features on digital maps and assess their LoD consistency. First, the contour of the geometry of the geographic feature is sketched and the hierarchy of its graphical units ...
Pengcheng Liu, Jia Xiao
doaj +1 more source
Probabilistic simulation for the certification of railway vehicles [PDF]
, 2015 The present dynamic certification process that is based on experiments has been essentially built on the basis of experience. The introduction of simulation techniques into this process would be of great interest.
Christine Funfschilling +9 more
core +3 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Numerical analysis of lifted hydrogen flame
MATEC Web of Conferences, 2018 A numerical analysis of a turbulent lifted H2/N2 flame is presented. As combustion mechanisms, a large spectrum is considered including single-step and two-step, as well as detailed mechanisms.
Iqbal Sohail +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
The effect of voltage on accuracy in electrochemical micromachining under two-tone sinusoidal signal
Electrochemistry CommunicationsElectrochemical micromachining (ECMM) is a non-traditional technology in the field of machining, which has excellent machining quality. Ultra short pulse power supply is widely used in electrochemical micro machining, and shortening the pulse width is ...
Xin Wang +3 more
doaj +1 more source
Business process simulation: An alternative modelling technique for the information system development process [PDF]
, 2006 This paper discusses the idea that even though information systems development (ISD) approaches have long advocated the use of integrated organisational views, the modelling techniques used have not been adapted accordingly and remain focused on the ...
Elliman, T, Hatzakis, T, Serrano, A
core