Results 41 to 50 of about 589,178 (317)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
From Processing-in-Memory to Processing-in-Storage
Supercomputing Frontiers and Innovations, 2017 Near-data in-memory processing research has been gaining momentum in recent years. Typical processing-in-memory architecture places a single or several processing elements next to a volatile memory, enabling processing without transferring data to the host CPU. The increased bandwidth to and from volatile memory leads to performance gain.
Roman Kaplan, Leonid Yavits, Ran Ginosar
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Frontiers in Human Neuroscience, 2019 Relatively little attention has been paid to the neural basis of superior memory despite its potential in providing important insight into efforts to improve memory in the general population or to offset age-related cognitive decline.
Jong-Sung Yoon +4 more
doaj +1 more source
Children's basic memory processes, stress and maltreatment [PDF]
, 2006 Building upon methods and research utilized with normative populations, we examine extant assumptions regarding the effects of child maltreatment on memory.
Howe, Mark L. +2 more
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Task switching involves working memory: Evidence from neural representation
Frontiers in Psychology, 2022 It is generally assumed that task switching involves working memory, yet some behavioral studies question the relationship between working memory and task switching ability.
Yanqing Wang +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hamiltonian characterization of multi-time processes with classical memory
New Journal of PhysicsA central problem in open quantum systems is the characterization of non-Markovian processes, where an environment retains the memory of its interaction with the system.
Kaumudibikash Goswami +6 more
doaj +1 more source