Results 81 to 90 of about 78,174,087 (302)

On parameter estimation for locally stationary long-memory processes [PDF]

open access: yes
We consider parameter estimation for time-dependent locally stationary long-memory processes. The asymptotic distribution of an estimator based on the local infinite autoregressive representation is derived, and asymptotic formulas for the mean squared ...
Jan Beran
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Testing Fractional Order of Long Memory Processes: A Monte Carlo Study [PDF]

open access: yes
Testing the fractionally integrated order of seasonal and nonseasonal unit roots is quite important for the economic and financial time series modeling. In this article, the widely used Robinson's (1994) test is applied to various well-known long memory ...
Zhiping Lu   +2 more
core   +2 more sources

An overview of the neuro-cognitive processes involved in the encoding, consolidation, and retrieval of true and false memories

open access: yesBehavioral and Brain Functions, 2012
Perception and memory are imperfect reconstructions of reality. These reconstructions are prone to be influenced by several factors, which may result in false memories.
Straube Benjamin
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Neural decoding reveals dynamic patterns of visual chunk memory processes

open access: yesBrain Research Bulletin
Chunk memory constitutes the basic unit that manages long-term memory and converts it into immediate decision-making processes, it remains unclear how to interpret and organize incoming information to form effective chunk memory.
Chantat Leong, Fei Gao, Zhen Yuan
doaj   +1 more source

Spurious Memory in Non-Equilibrium Stochastic Models of Imitative Behavior

open access: yesEntropy, 2017
The origin of the long-range memory in non-equilibrium systems is still an open problem as the phenomenon can be reproduced using models based on Markov processes. In these cases, the notion of spurious memory is introduced.
Vygintas Gontis, Aleksejus Kononovicius
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Anterograde and Retrograde Effects of Benzodiazepines on Memory

open access: yesThe Scientific World Journal, 2006
Benzodiazepines are known as “acquisition-impairing” molecules, and their effects on anterograde memory processes are well described. In contrast, the impact of benzodiazepines on retrograde memory and, more particularly, on retrieval processes, is only ...
Daniel Beracochea
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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