Results 91 to 100 of about 684,002 (265)

Hot Deformation Behavior and Processing Maps of an As-Cast Al-5Mg-3Zn-1Cu (wt%) Alloy. [PDF]

Materials (Basel), 2023
Lei C, Wang Q, Ebrahimi M, Li D, Tang H, Zhang N, Cai H.   +6 more
europepmc   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Hot Formability Study of Cr5 Alloy Steel by Integration of FEM and 3D Processing Maps. [PDF]

Materials (Basel), 2022
Chen X, Si Y, Bai R, Zhang X, Li Z.
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Strategies for automatic generation of information processing pathway maps

Frontiers in Neuroimaging
Information Processing Pathway Maps (IPPMs) are a concise way to represent the evidence for the transformation of information as it travels around the brain.
Anirudh Lakra, Cai Wingfield, Cai Wingfield, Chao Zhang, Chao Zhang, Chao Zhang, Chao Zhang, Andrew Thwaites, Andrew Thwaites   +8 more
doaj   +1 more source

Hot Deformation Behavior, Processing Maps and Microstructural Evolution of the Mg-2.5Nd-0.5Zn-0.5Zr Alloy. [PDF]

Materials (Basel), 2022
Ma J, Wang S, Yang J, Zhang W, Chen W, Cui G, Chu G.   +6 more
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Hot Deformation Behavior and Processing Maps of a New Ti-6Al-2Nb-2Zr-0.4B Titanium Alloy. [PDF]

Materials (Basel), 2021
Yang Z, Yu W, Lang S, Wei J, Wang G, Ding P.   +5 more
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Deformation Behavior, a Flow Stress Model Considering the Contribution of Strain and Processing Maps in the Isothermal Compression of a Near-α Ti-3.3Al-1.5Zr-1.2Mo-0.6Ni Titanium Alloy. [PDF]

Materials (Basel), 2022
Yu W, Cao J, Hou S, Wang G, Li Y, Lang S.   +5 more
europepmc   +1 more source