Results 91 to 100 of about 711,244 (265)
Mapping the Information System Development Process [PDF]
, 2005 Action research is used to gain understanding of how an IS development methodology emerges in practice and how it can contribute to value creation in organizations. The Multiview framework is used to guide the action research project. A graphical notation for mapping the unfolding of IS development projects is developed and applied to the project ...
Vidgen, Richard +2 more
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Effect of Er on the Hot Deformation Behavior of the Crossover Al3Zn3Mg3Cu0.2Zr Alloy
MetalsThe effect of an erbium alloying on the hot deformation behavior of the crossover Al3Zn3Mg3Cu0.2Zr alloy was investigated in detail. First of all, Er increases the solidus temperature of the alloy. This allows hot deformation at a higher temperature. The
Maria V. Glavatskikh +6 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Deformation Mechanisms and Processing Maps for High Entropy Alloys (Presentation of Processing Maps in Terms of Zener-Hollomon Parameter): Review. [PDF]
Materials (Basel), 2023 Jeong HT, Kim WJ.
europepmc +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Hot Deformation Behavior and Processing Maps of 26CrMo7S Steel Used in Oil Exploration. [PDF]
Materials (Basel), 2023 Jiang H +7 more
europepmc +1 more source
Hot Deformation and Processing Maps of 7005 Aluminum Alloy
High Temperature Materials and Processes, 2014 The deformation behavior of 7005 alloy was studied by hot compression tests. The processing map was constructed by superimposing the instability map over the power dissipation map at a strain of 0.7 using the corrected flow stress data to eliminate the ...
Wang Mingliang, Jin Peipeng, Wang Jinhui
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source