Results 151 to 160 of about 552,845 (263)

Multimodal predictors of disability progression and processing speed decline in relapsing-remitting multiple sclerosis. [PDF]

Sci Rep
Korbmacher M, Lie IA, Wesnes K, Westman E, Espeseth T, Specht K, Andreassen OA, Westlye LT, Wergeland S, Myhr KM, Torkildsen Ø, Høgestøl EA.   +11 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Temporally Defined Brain Network Activation Associated With Slowed Information Processing Speed in Multiple Sclerosis. [PDF]

Hum Brain Mapp
Burta O, Akbarian F, Rossi C, Vidaurre D, D'hooghe MB, D'Haeseleer M, Nagels G, Van Schependom J.   +7 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Robotic rehabilitation with the Lokomat^® system in the improvement of executive functions and processing speed in stroke patients: a quasi-experimental study. [PDF]

Front Aging Neurosci
Cabrera-Brito ME, Carcelén-Fraile MDC, Aibar-Almazán A, Márquez-Apolinario MA, Castellote-Caballero Y.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Baseline Oculomotor Parameters Are Prospectively Associated with Cognitive Processing Speed at 6-Year Follow-Up in Multiple Sclerosis: An Exploratory Cohort Study. [PDF]

J Clin Med
Ruiz-Ortiz M, García-Cena C, Hernández-Ramírez R, Moreno-García S, Labiano-Fontcuberta A, Montabes-Medina P, Álamo-Díez MD, Guzmán-Villamarín DE, Benito-León J.   +8 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Processing speed impairment after anterior communicating artery aneurysm rupture assessed using the wechsler adult intelligence scale: an observational study. [PDF]

BMC Neurol
Okui T, Otani N, Iwata T, Beppu K, Horii R, Kajikawa R, Tsuzuki T.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source