Results 51 to 60 of about 4,839,172 (251)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Episodic and semantic memory functioning in very old age: Explanations from executive functioning and processing speed theories

open access: yesCogent Psychology, 2015
Structural equation modeling was used to investigate whether age-related episodic and semantic memory impairments are better explained by decline in processing speed or executive functioning (or both), rather than directly in terms of memory components ...
Pauline E.J. Spaan
doaj   +1 more source

Paper-Based Assessment of the Effects of Aging on Response Time: A Diffusion Model Analysis

open access: yesJournal of Intelligence, 2017
The effects of aging on response time were examined in a paper-based lexical-decision experiment with younger (age 18–36) and older (age 64–75) adults, applying Ratcliff’s diffusion model. Using digital pens allowed the paper-based assessment of response
Judith Dirk   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Temporal Aspects of Memory: A Comparison of Memory Performance, Processing Speed and Time Estimation Between Young and Older Adults

open access: yesFrontiers in Aging Neuroscience, 2018
Cognitive abilities are often reported to decline across the lifespan, particularly when assessed with working memory (WM) measures such as the auditory backward digit span and complex N-back tasks.
Deena Ebaid, Sheila G. Crewther
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An anisotropic lattice Boltzmann - phase field model for dendrite growth and movement in rapid solidification of binary alloys

open access: yesnpj Computational Materials
A model coupling the lattice Boltzmann and the phase field methods with anisotropic effects is proposed, which is used to numerically describe the growth and movement of dendrites in rapid solidification of alloys.
Shilin Mao   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Relation of working memory updating to processing speed in cognitive aging

open access: yes, 2004
The study was conducted to investigate the roles of working memory updating in cognitive aging and its relation to processing speed. 142 adults between 18 and 85 years of age performed a set of updating, processing speed, and fluid cognitive tasks.
T. Y. Chen, D. M. Li
core   +1 more source

Comprehension of familiar and unfamiliar native accents under adverse listening conditions [PDF]

open access: yes, 2009
This study aimed to determine the relative processing cost associated with comprehension of an unfamiliar native accent under adverse listening conditions. Two sentence verification experiments were conducted in which listeners heard sentences at various
Stuart-Smith, J.   +3 more
core   +1 more source

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