Results 31 to 40 of about 15,198 (259)

Closed-Loop Spiking Control on a Neuromorphic Processor Implemented on the iCub [PDF]

IEEE Journal on Emerging and Selected Topics in Circuits and Systems, 2020
Despite neuromorphic engineering promises the deployment of low latency, adaptive and low power systems that can lead to the design of truly autonomous artificial agents, the development of a fully neuromorphic artificial agent is still missing. While neuromorphic sensing and perception, as well as decision-making systems, are now mature, the control ...
Zhao, Jingyue, Risi, Nicoletta, Monforte, Marco, Bartolozzi, Chiara, Indiveri, Giacomo, Donati, Elisa   +5 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Real time implementation for robust adaptive sliding mode predictive control of PMSM

Unconventional Resources
Model Predictive Control is recognized as a promising approach for electric drives, with particular interest in the development of robust and high-performance predictive models.
Rachid Ibrahimi, Mohamed said Adouairi, Abdennabi Morchid, Badre Bossoufi, Paweł Skruch, Saleh Mobayen   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Exploiting loop-dependent stream reuse for stream processors [PDF]

Proceedings of the 17th international conference on Parallel architectures and compilation techniques, 2008
The memory access limits the performance of stream processors. By exploiting the reuse of data held in the Stream Register File (SRF), an on-chip storage, the number of memory accesses can be reduced. In current stream compilers reuse is only attempted for simple stream references, those whose start and end are known.
Xuejun Yang, Ying Zhang 0032, Jingling Xue, Ian Rogers, Gen Li 0002, Guibin Wang   +5 more
openaire   +1 more source

A Digital Twin Approach for Spacecraft On-Board Software Development and Testing

Aerospace
The increasing complexity of spacecraft On-Board Software (OBSW) necessitates advanced development and testing methodologies to ensure reliability and robustness.
Andrea Colagrossi, Stefano Silvestrini, Andrea Brandonisio, Michèle Lavagna   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source