Results 91 to 100 of about 41,499 (247)

Binding of Procollagen C-Proteinase Enhancer-1 (PCPE-1) to Heparin/Heparan Sulfate

Journal of Biological Chemistry, 2010
Procollagen C-proteinase enhancer-1 (PCPE-1) is an extracellular matrix (ECM) glycoprotein that can stimulate procollagen processing by procollagen C-proteinases (PCPs) such as bone morphogenetic protein-1 (BMP-1).
T. Weiss, S. Ricard-Blum, L. Moschcovich, Eitan Wineman, Shlomit Mesilaty, E. Kessler   +5 more
semanticscholar   +1 more source

Galectin‐3 plasma levels are associated with left atrial contractile function in long‐distance runners

Experimental Physiology, EarlyView.
Abstract High‐intensity endurance exercise induces myocardial remodelling as an adaptive response to sustained volume overload, but excessive cumulative training might also favour deleterious cardiac remodelling, including atrial fibrosis. Whether acute marathon running engages circulating fibrosis‐related biomarkers and whether these biomarkers track ...
Felipe Contreras‐Briceño, Fernanda Sanhueza‐Olivares, Rodrigo Fernández, Silvana Llevaneras, Pablo F. Castro, Luigi Gabrielli, Mario Chiong   +6 more
wiley   +1 more source

Cell-free Generation of COPII-coated Procollagen I Carriers

Bio-Protocol, 2017
The aim of this protocol is to generate COPII-coated procollagen I (PC1) carriers in a cell-free reaction. The COPII-coated PC1 carriers were reconstituted from donor membrane, cytosol, purified recombinant COPII proteins, and nucleotides.
Lin Yuan, Satoshi Baba, Kanika Bajaj, Randy Schekman   +3 more
doaj   +1 more source

BMP-2 and TGF-β1 differentially control expression of type II procollagen and α10 and α11 integrins in mouse chondrocytes

European Journal of Cell Biology, 2010
Bone morphogenetic protein (BMP)-2 and transforming growth factor (TGF)-β1 are multifunctional cytokines both proposed as stimulants for cartilage repair. Thus it is crucial to closely examine and compare their effects on the expression of key markers of
J. Gouttenoire, C. Bougault, E. Aubert-Foucher, Emeline Perrier, M. Ronzière, L. Sandell, E. Lundgren-Åkerlund, F. Mallein-Gerin   +7 more
semanticscholar   +1 more source

Variants at 8p21.3 Mediate BMP1 Expression, Contributing to Higher Atopic Dermatitis Risk

Clinical &Experimental Allergy, EarlyView.
Jia Yi Karen Wong, Yang Yie Sio, Yi Ying Eliza Lim, Yee‐How Say, Kavita Reginald, Fook Tim Chew   +5 more
wiley   +1 more source

Effects of 14 days of head‐down bed rest with or without exercise, and subsequent recovery on bone turnover, density and structure in older adults

Experimental Physiology, EarlyView.
Abstract Bed rest accelerates bone loss and may exacerbate skeletal fragility. This study examined the effects of 14 days of head‐down tilt bed rest (HDBR) with or without exercise, and subsequent recovery, on bone turnover, density and structure in older adults. Twenty‐two healthy older adults (55–65 years) completed the HDBR protocol.
Guy Hajj‐Boutros, Andréa Faust, Carmelo Mastrandrea, Vita Sonjak, Dounia Rouabhia, Gustavo Duque, Richard Kremer, Stéphanie Chevalier, Julie Lacombe, Mathieu Ferron, Tyler A. Churchward‐Venne, José A. Morais   +11 more
wiley   +1 more source

Endocrine and androgenic response to altitude training in professional cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss, Bastien Krumm, Claes Cubel, Magnus Bak Klaris, Lasse Vestli Baekken, Yvette Dehnes, Jenna Goodrum, Geoff Miller, James Spragg, Martin Faulhaber, Francesco Botrè, Carsten Lundby   +11 more
wiley   +1 more source

Genes Associated With Fracture Risk in Thoroughbred Horses Have Novel Roles in Osteogenesis

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Bone fractures in Thoroughbred racehorses are a major welfare problem. Genetic factors contribute to fracture risk. Cell models have previously identified 112 differentially expressed genes in bone‐forming osteoblasts derived from horses at high and low genetic risk of fracture. However, 42 of these genes have no published role in bone.
Amy C. Ross, Ellison S. Lumsden, Caroline Flood, Jayesh Dudhia, Androniki Psifidi, Deborah J. Guest   +5 more
wiley   +1 more source

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 334-344, August 2026.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source

Plasma Extracellular Vesicles‐Derived Complement Proteins as Biomarkers of Sarcopenia Progression in Longitudinal Cohorts

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Sarcopenia is characterized by progressive loss of muscle mass, strength and physical performance, yet current diagnostic tools are limited for practical and longitudinal monitoring. Extracellular vesicles (EVs) encapsulate various biomolecules, including proteins, nucleic acids, lipids and metabolites and have emerged as promising ...
Ji Yeon Kim, Sung Hye Kong, Dohyun Han, Tae‐Hwan Gil, Hyeon Soo Kim, Miji Kim, Jin Hee Kim, Seung Shin Park, Seong‐Jun Park, Hak Chul Jhang, Chang Won Won, Ok Hee Jeon   +11 more
wiley   +1 more source