Results 221 to 230 of about 18,771 (276)

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

open access: yesAdvanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen   +14 more
wiley   +1 more source

Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs

open access: yesAdvanced Science, EarlyView.
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang   +13 more
wiley   +1 more source

End of Life Assistance (Scotland) Bill [PDF]

open access: yes, 2010
Laurie, Graeme, Mason, Ken
core  

AP‐Lab: An AI‐Driven Autonomous Pilot‐Scale Platform Bridging Materials Discovery and Industrial Manufacturing

open access: yesAdvanced Science, EarlyView.
AP‐Lab bridges materials discovery and industrial manufacturing by coupling proprietary datasets with an application benchmark (PCR Ct). A closed‐loop optimization workflow integrates ML, LLM, and autonomous synthesis/testing to refine magnetic nanoparticles–based nucleic‐acid extraction systems.
Zhan‐Long Wang   +12 more
wiley   +1 more source

New drug controls and reduced hospital presentations due to novel psychoactive substances in Edinburgh. [PDF]

open access: yesBr J Clin Pharmacol, 2018
Pettie J   +10 more
europepmc   +1 more source

Improving the Thermoelectric Properties of Conjugated Polymer Thin Films by Dip Coating – but not through Alignment

open access: yesAdvanced Electronic Materials, EarlyView.
The study demonstrates that dip coating at lower speeds significantly enhances the thermoelectric performance of P3HT by improving electrical conductivity. Contrary to expectations, this improvement is seemingly not due to polymer alignment but rather to better structural order achieved during slower solvent evaporation at lower dip coating speeds ...
Morteza Shokrani   +2 more
wiley   +1 more source

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