Results 31 to 40 of about 18,838 (296)

Ties of resistance and cooperation: Aedemon, Lusius Quietus and the Baquates [PDF]

, 2013
Gaius' decision to dissolve the protectorate of Mauretania and to depose its client king, Ptolemaeus, led to the outbreak of the Revolt of Aedemon (AD 40).
Vanacker, Wouter
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Nikitin Case: Rule of Law? [PDF]

, 1996
Condette Jean-François. 252) MALPEL François Frédéric. In: , . Les recteurs d'académie en France de 1808 à 1940. Tome II, Dictionnaire biographique. Paris : Institut national de recherche pédagogique, 2006. p. 271.
Lohman, Diederik
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Procurator or Prefect – remarks on the administration of Roman provinces in the context of Pontius Pilate's title

Journal of Modern Science
Objectives The research problem concerns whether Pontius Pilate (who was the governor of Judea in 26-36 CE) served as procurator (as indicated by Tacitus) or perhaps as prefect (as indicated by epigraphic sources).
Wojciech Jan Kosior
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Financial provision of employees in RSFSR regional procuracies in 1955-1964 (on materials of Pskov region procuracy)

Studia Humanitatis, 2018
The article reviews the problem of financial support for employees of the regional procuracies of the RSFSR during the Khrushchev's Thaw (1955-1964).
Frolov Vasiliy Vladimirovich
doaj  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Menorah (No. 2, Winter, 1985) [PDF]

, 1985
Reflections On Membership -- Selma And Jacob Brown Annual Lectureship Established -- Deconstructing Jewish Consciousness -- Centaurs -- Death of a Charismatic -- Metaphysical Knot -- New VCU Course ...

core   +1 more source