Results 221 to 230 of about 10,740,998 (244)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Copathologies of Limbic-Predominant Age-Related TDP-43 Encephalopathy and Alzheimer Disease: [<sup>18</sup>F]FDG PET Statistical Mapping and Quantitative MRI Volumetry. [PDF]

open access: yesJ Nucl Med
Ngam PI   +7 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Mild Direct Remote Hydroxylation of Enals in Air. [PDF]

open access: yesJ Org Chem
Liu F, Vicidomini A, Brenner-Moyer SE.
europepmc   +1 more source

Allocation in field crop and livestock life cycle assessment. [PDF]

open access: yesInt J Life Cycle Assess
Bamber N, Kroebel R, Pelletier N.
europepmc   +1 more source

Potential of Sentinel-3 snow cover fraction data for improving hydrological simulations at the regional scale. [PDF]

open access: yesSci Rep
Tanhapour M   +7 more
europepmc   +1 more source

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