A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Copathologies of Limbic-Predominant Age-Related TDP-43 Encephalopathy and Alzheimer Disease: [<sup>18</sup>F]FDG PET Statistical Mapping and Quantitative MRI Volumetry. [PDF]
Ngam PI +7 more
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Mild Direct Remote Hydroxylation of Enals in Air. [PDF]
Liu F, Vicidomini A, Brenner-Moyer SE.
europepmc +1 more source
Allocation in field crop and livestock life cycle assessment. [PDF]
Bamber N, Kroebel R, Pelletier N.
europepmc +1 more source
The live-streaming strategy for competitive manufacturers considering information disclosure and product heterogeneity. [PDF]
Liu L, Wang Q, Li Z, Wu T, Yuan Y.
europepmc +1 more source
Potential of Sentinel-3 snow cover fraction data for improving hydrological simulations at the regional scale. [PDF]
Tanhapour M +7 more
europepmc +1 more source
Testing the effects of nutrition-related claims on perceptions of and preferences for alcohol products among Australian consumers. [PDF]
Yusoff A +5 more
europepmc +1 more source
Dearomatization of Aromatic Carbonyl Compounds by Photocycloaddition Reactions to 1,1-Dimethylallene. [PDF]
Oxenfart L +3 more
europepmc +1 more source

