Results 61 to 70 of about 2,735,014 (284)

Authentication and Authorization in Microservice-Based Applications

open access: yes, 2022
The development of microservice-based applications adds challenges when using different cloud services. One such challenge is the integration of authentication and authorization among different systems. In this publication, we describe the development of
Abeck,Sebastian, Sänger,Niklas
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

The application of portable NIR spectroscopy for food authentication and quality control

open access: yesJurnal Teknologi & Industri Hasil Pertanian
Food authentication and quality control have become major challenges in the global food industry, particularly due to issues of food adulteration that impact consumer health and product integrity in the market.
Widyaningrum, Sakinah Ahyani Dahlan
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Digital fragile watermarking scheme for authentication of JPEG images [PDF]

open access: yes, 2004
It is a common practice in transform-domain fragile watermarking schemes for authentication purposes to watermark some selected transform coefficients so as to minimise embedding distortion.
C.-T. Li, Li, Chang-Tsun
core   +1 more source

The Authenticity of Cultural Products: A Psychological Perspective

open access: yesCurrent Directions in Psychological Science, 2017
Authenticity is a central concern in the evaluation of cultural products. But why do people judge some cultural products as more authentic than others? We provide a psychological explanation centered on the judgment of authenticity as a “truth-seeking” process.
Kreuzbauer, Robert, Keller, J
openaire   +4 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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