Results 41 to 50 of about 390,939 (260)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Improved Single-Shot Decoding of Higher-Dimensional Hypergraph-Product Codes
PRX Quantum, 2023 In this work, we study the single-shot performance of higher-dimensional hypergraph product codes decoded using belief propagation and ordered-statistics decoding [P. Panteleev and G. Kalachev, Quantum 5, 585 (2021)]. We find that decoding data-qubit and
Oscar Higgott, Nikolas P. Breuckmann
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
MDR codes and self-dual codes on Cartesian product codes
Tongxin xuebao, 2010 A Cartesian product code of the linear codes C1 , , C s in 1 , ,Z r Z rs was defined. According to the theorem of submodulo isomorphism, the relationship between the rank of the Cartesian product code C1 × C 2 × × Cs over Z r1 × Z r2 × × Zrsand C1 , C 2,
LIU Xiu-sheng
doaj +2 more sources
The Implementation of QR-Code Technology on Bulak Fish Center Information System
JOIN: Jurnal Online Informatika, 2019 The technology that is currently developing is the use of QR-Code. QR-Code can convey information quickly with the acquisition of fast responses as well. QR-Code can be used on smartphones. Some media and companies widely use the QR-Code in Indonesia. QR-
Febri Liantoni +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Twisted tensor product codes [PDF]
Designs, Codes and Cryptography, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source