Results 51 to 60 of about 390,939 (260)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Digital filter optimization for C language

open access: yesAdvances in Electrical and Computer Engineering, 2011
A method for transforming C code with floating-point values into C code with integer variables is developed. The objective is to avoid any operations with floating-point data types, thereby increasing the execution speed of the program on a ...
BARLEANU, A., BAITOIU, V., STAN, A.
doaj   +1 more source

Qudit homological product codes [PDF]

open access: yesQuantum Information and Computation, 2017
In this note we show that the random homological product code construction of Bravyi and Hastings can be extended to qudits of dimension D with D an odd prime. While the result is not surprising, the proof does require new ideas.
Máté Farkas, Péter Vrana
openaire   +3 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

The weight hierarchy of product codes

open access: yesIEEE Transactions on Information Theory, 2000
Summary: The weight of a code is the number of coordinate positions where no codeword is zero. The \(r\)th minimum weight \(d_r\) is the least weight of an \(r\)-dimensional subcode. \textit{V. K. Wei} and \textit{K. Yang} [ibid. 39, 1709-1713 (1993; Zbl 0801.94016)] gave a conjecture about the minimum weights for some product codes.
openaire   +3 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Rapid computation and visualization of data from Kano surveys in R

open access: yesBMC Research Notes, 2018
Objective The Kano model for user satisfaction is a popular survey-based method used by product designers to prioritize the inclusion and implementation of product features based on users’ requirements.
Reynir S. Atlason, Davide Giacalone
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

DECOMPOSABLE SEC-DED CODES OF ENHANCED AUGMENTED PRODUCT CODE CONSTRUCTION

open access: yesElectrica, 2003
Enhanced augmented product code construction (EAPCC) and its decomposable SEC-DED (single- error-correcting/double-error-detecting) codes, which are composed by augmenting the simple component codes (2,1,2) and (2,1,1) on to a two dimensional general ...
Gökmen ALTAY
doaj   +2 more sources

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