Retracted: Fuzzy Logic-Based Machine Learning Algorithm for Cultural and Creative Product Design. [PDF]
Comput Intell Neurosci, 2023 Intelligence And Neuroscience C.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Preliminary of User Interface Design for Picture Archiving and Communication System
, 2013 [[abstract]]In order to gain entry to modern and technology, medical imaging technology not only has to economically storing, and conveniently accessing, images from multiple modalities, but also focus on user’s experience and interaction.
Lin, Wei-Chun Winine;Lee, Yuan-Zone
core
A quantitative framework for translating architectural heritage into cultural product design through ancient theatrical stages in Shanxi. [PDF]
Sci RepSun F, Zhang X, Zhang L.
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Insights into product design students' perception of, and engagement with, creativity in design education. [PDF]
Int J Technol Des Educ, 2023 McInerney D.
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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Being Concerned with Substances of Concern: A Classification of Ethical Dilemmas in Circular Product Design. [PDF]
Sci Eng EthicsKrstulović I.
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Evaluating the Efficacy of Sunscreen Formulas in Reducing UV Filter Permeation Into the Stratum Corneum via In Vivo Confocal Raman Spectroscopy: Insights and Applications for Practical Suncare Product Design. [PDF]
Photodermatol Photoimmunol PhotomedZhang T +8 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source