Results 161 to 170 of about 12,719,567 (285)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Product design improvement method driven by online product reviews. [PDF]

Sci Rep
Cheng FM, Wang J, Chen C, Hu GR, Cao ZJ.
europepmc   +1 more source

An evaluation method for product design solutions for healthy aging companionship. [PDF]

Front Public Health, 2022
Hu S, Jia Q, Dong L, Han J, Guo M, Guo W.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Research on product design priority allocation based on user characteristics classification. [PDF]

Sci Rep
Wang Y, He J, Yang W, Kim KS.
europepmc   +1 more source

How Industry 4.0 and Sensors Can Leverage Product Design: Opportunities and Challenges. [PDF]

Sensors (Basel), 2023
Rosário AT, Dias JC.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Assessment of a Bioengineering and Nursing Student Partnership for Medical Product Design. [PDF]

Biomed Eng Educ
Clark RM, Dukes AA, Sowko L, Gartner M.
europepmc   +1 more source

Promoting active aging through assistive product design innovation: a preference-based integrated design framework. [PDF]

Front Public Health, 2023
Zhang B, Ma M, Wang Z.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source