Results 51 to 60 of about 4,767,137 (292)

Design of a Self-Reconfigurable Drain Mapping Robot With Level-Shifting Capability

open access: yesIEEE Access, 2020
Nature has always been an inspiration for engineers and designers to have technological inventions. The postures, locomotion and gait cycles of animals are usually smooth, dynamically stable, and highly adaptable in an unknown terrain. Based on a giraffe'
Rizuwana Parween   +5 more
doaj   +1 more source

A metaheuristic approach to optimal morphology in reconfigurable tiling robots

open access: yesComplex & Intelligent Systems, 2023
Reconfigurable robots are suitable for cleaning applications due to their high flexibility and ability to change shape according to environmental needs.
Manivannan Kalimuthu   +4 more
doaj   +1 more source

Exploiting supplier capabilities to maximise product design opportunities in the fuzzy front end activities [PDF]

open access: yes, 2013
This paper explores the Fuzzy Front-End (FFE), i.e. the first phase of the Product Design and Development process where a company formulates a product concept to be developed and decides whether or not to invest resources in the further development of an
Bolton, Simon   +3 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

MODELLING SYNERGISTIC EYE MOVEMENTS IN THE VISUAL FIELD

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
Some theoretical and practical considerations about eye movements in visual field are presented in the first part of this paper. These movements are developed into human body to be synergistic and are allowed to obtain the visual perception in 3D space ...
BARITZ Mihaela, BRAUN Barbu
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Gaming techniques and the product development process : commonalities and cross-applications [PDF]

open access: yes, 2006
The use of computer-based tools is now firmly embedded within the product development process, providing a wide range of uses from visualisation to analysis.
Bradley, D., Wodehouse, A.J.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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