Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
An empirical investigation into the use of product development in the educational furniture industry : a thesis presented in fulfilment of the requirements for the Master of Technology in Product Development at Massey University, Palmerston North, New Zealand [PDF]
, 2001 An empirical investigation into the use of product development in the educational furniture industry is summarised in this thesis. New Zealand furniture manufacturers are facing increased competition from imported furniture and are also exporting more ...
Morgan, Jeffrey Martin
core
Addressing decision making for remanufacturing operations and design-for-remanufacture [PDF]
, 2009 Remanufacturing is a process of returning a used product to at least original equipment manufacturer original performance specification from the customers' perspective and giving the resultant product a warranty that is at least equal to that of a newly ...
Amezquita T. +14 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Reconfigurable Robotic Exercising Companion
Applied SciencesRegular exercise plays a crucial role in promoting overall well-being in today’s lifestyle. However, individuals often find it challenging to properly execute exercises, including maintaining correct postures and appropriate movement speeds.
W. K. R. Sachinthana +4 more
doaj +1 more source
Sensors, 2016 In this work, we present a novel microfluidic biosensor for sensitive fluorescence detection of DNA based on 3D architectural MoS2/multi-walled carbon nanotube (MWCNT) nanocomposites.
Dahou Yang +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cascaded Machine-Learning Technique for Debris Classification in Floor-Cleaning Robot Application
Applied Sciences, 2018 Debris detection and classification is an essential function for autonomous floor-cleaning robots. It enables floor-cleaning robots to identify and avoid hard-to-clean debris, specifically large liquid spillage debris.
Balakrishnan Ramalingam +4 more
doaj +1 more source
Knowledge creation and visualisation by using trade-off curves to enable set-based concurrent engineering [PDF]
, 2016 The increased international competition forces companies to sustain and improve market share through the production of a high quality product in a cost effective manner and in a shorter time.
Al-Ashaab, Ahmed +2 more
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source