Results 111 to 120 of about 26,594,875 (325)

A product line for workflow management systems [PDF]

open access: yes, 2004
This paper presents an ongoing research on the development of a component-based product line architecture for workflow management systems. The research includes a process to design the proposed product line, the population of the product with components,
Barroca, Leonor   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

P852: NEOANTIGENS PREDICTED BY THE GNE NEOANTIGEN PIPELINE IN PATIENTS DIAGNOSED WITH DE NOVO MULTIPLE MYELOMA

open access: yesHemaSphere, 2022
Y. Jiang   +8 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Product Development in the World Auto Industry [PDF]

open access: yes
macroeconomics, auto industry, management efficiency ...
Kim B. Clark   +2 more
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Area-Efficient Decimation Filter with 50/60Hz Power-Line Noise Suppression for ΔΣ A/D Converters

open access: yesSICE Journal of Control, Measurement, and System Integration, 2017
This paper introduces a new digital filter utilizing a SINC filter used in ΔΣ A/D converters and featuring 50/60Hz power-line noise rejection.
Hideki Kuribayashi, Tetsuya Kajita
doaj   +1 more source

Value stream mapping to reduce the lead-time of a product development process

open access: yes, 2015
Product development (PD) is a broad field of endeavor dealing with the planning, design, creation, and marketing of a new product. This revolutionary research domain has become of paramount importance to beat the competition for multidisciplinary ...
S. Tyagi   +3 more
semanticscholar   +1 more source

Approaching a reliable process simulation for the virtual product development [PDF]

open access: yes, 2005
In this paper an outline for a strategy to include manufacturing effects in subsequent\ud simulations for the virtual product development from an industrial point of view is given.\ud Especially the conditions for a successful mapping of geometry and ...
Bessert, N.   +3 more
core   +1 more source

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