Results 251 to 260 of about 18,644,533 (316)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Navigating regulatory and analytical challenges in live biotherapeutic product development and manufacturing. [PDF]

Front Microbiomes
Microbiome Therapeutics Innovation Group, Barberio D.   +1 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and its Regulatory Utility to Support Oral Drug Product Development and Harmonization. [PDF]

Pharm Res
Cheng YH, Thomas S, Tsang YC, Almeida S, Ashraf M, Fotaki N, Heimbach T, Patel N, Shah H, Jiang X, Kim MJ, Moody R, Rostami-Hodjegan A, Singh R, Zhao L, Babiskin A, Wu F.   +16 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

OmicShare tools: A zero‐code interactive online platform for biological data analysis and visualization

iMeta
Hongyan Mu, Jianzhou Chen, Wenjie Huang, Gui Huang, Meiying Deng, Shimiao Hong, Peng Ai, Chuan Gao, Huangkai Zhou   +8 more
doaj   +1 more source

Psychological Resources and New Product Development Team Adaptability: A Moderated Mediation Model. [PDF]

Small Group Res
Marques DL, Aubé C, Rousseau V, Brunelle E.   +3 more
europepmc   +1 more source

Comparison of biological properties of human adipose tissue-derived mesenchymal stem/ stromal cells from healthy and diabetic donors: consequences for cell-based medicinal product development. [PDF]

Cardiovasc Diabetol
Dudek P, Łabędź-Masłowska A, Madeja Z, Zuba-Surma E.   +3 more
europepmc   +1 more source

Bioengineering breakthroughs: The impact of stem cell models on advanced therapy medicinal product development. [PDF]

World J Stem Cells
Granjeiro JM, Borchio PGM, Ribeiro IPB, Paiva KBS.   +3 more
europepmc   +1 more source

Research Progress on Active Ingredients and Product Development of Lycium ruthenicum Murray. [PDF]

Molecules
Xu ML, He YF, Xie L, Qu LB, Xu GR, Cui CX.   +5 more
europepmc   +1 more source