Results 101 to 110 of about 1,694,885 (313)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2012 One of the most distinct aspects of creativity in design is an aesthetic sense, an indubitable determinant of product success in the market. It is therefore of great importance to nurture creativity in terms of formal aesthetics in design education ...
Rahe, Ulrike, +2 more
core
Product strategies and startups' survival in turbulent industries: evidence from the security software industry [PDF]
, 2004 This paper seeks to explore the drivers of startups' survival in turbulent industries, characterized by high rates of entry and exit, fragmented market shares, and a rapid pace of product innovation.
Fosfuri, Andrea +3 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Coordinating Tasks in M-Form and U-Form Organisations [PDF]
We model the coordination of specialised tasks inside an organisation as "attribute matching". Using this method, we compare the performance of organisational forms (M-form and U-form) in implementing changes such as innovation and reform.
Gerard Roland, Yingyi Qian, Chenggang Xu
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Product Form of the Inverse Revisited.
, 2012 Using the simplex method (SM) is one of the most effective ways of solving large scale real life linear optimization problems. The efficiency of the solver is crucial. The SM is an iterative procedure, where each iteration is defined by a basis of the constraint set. In order to speed up iterations, proper basis handling procedures must be applied. Two
Tar, Péter, Maros, István
openaire +3 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source