Results 41 to 50 of about 9,267 (212)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Natural Rubber–Based Adhesive Dressing Enriched With Rhodomyrtus tomentosa Leaf Extract Exhibiting Antioxidant, Anti-Inflammatory, and Antibacterial Activities Against Acne-Causing Bacteria

Advances in Pharmacological and Pharmaceutical Sciences
An acne treatment patch was developed by incorporating Rhodomyrtus tomentosa (RT) leaf extract into hyaluronic acid serum, followed by integration with high-quality block natural rubber using a two-roll milling process. RT hyaluronic acid serum exhibited
Apisit Chompraman, Sakkarin Lethongkam, Siwaporn Bilhman, Mareena Daus, Supayang Piyawan Voravuthikunchai, Supakit Paosen   +5 more
doaj   +1 more source

Product Innovation Influence on Production Organization

, 2018
This article deals with individual product innovations and their influence on production workplace and the technological production process. This work firstly deals with the current scientific knowledge, followed by the research itself, which defines the individuals inputs - product innovations and then the individual links between these innovations ...
Polášek, Patrik, Šimon, Michal
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A Framework of Product Attributes Analysis for Co-Creation [PDF]

International Journal of Industrial Engineering and Production Research, 2021
In the last decade, customers’ active involvement during product development, commonly referred to as co-creation, has emerged as an effective tool to overcome barriers that keep firms from understanding customer needs.
Faisal Rasool, Pisut Koomsap, Emérancia Raharisoa, Abdul Qayoom   +3 more
doaj   +1 more source

A model of the supplier involvement in the product innovation [PDF]

Yugoslav Journal of Operations Research, 2017
In this paper we examine the product innovation in a supply chain by a supplier and derive a model for a supplier’s product innovation policy. The product innovation of a supplier can contribute to the long-term competitiveness for the supply ...
Kumar Manoj, Raman Jyoti, Raman Priya
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Functional significance of commonly regulated genes in mechanically and chemically induced retinal ganglion cell death in rat eyes

Scientific Reports
Despite much effort, the molecular mechanisms of retinal ganglion cell (RGC) death remain unclear. To identify common cell death-promoting machinery in the mechanically and chemically injured retina, we profiled temporal gene expression patterns and ...
Masaaki Kageyama, Koji Ohashi, Takashi Ota   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

INNOVATION PRODUCTION MODELS

MGIMO Review of International Relations, 2016
The article is dedicated to the study of the models of production of innovations at enterprise and state levels. The shift towards a new technology wave induces a change in systems of division of labour as well as establishment of new forms of cooperation that are reflected both in theory and practice of innovation policy and management.
openaire   +5 more sources