Results 51 to 60 of about 427,530 (307)
Product Innovation Influence on Production Organization
, 2018 This article deals with individual product innovations and their influence on production workplace and the technological production process. This work firstly deals with the current scientific knowledge, followed by the research itself, which defines the individuals inputs - product innovations and then the individual links between these innovations ...
Polášek, Patrik, Šimon, Michal
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Framework of Product Attributes Analysis for Co-Creation [PDF]
International Journal of Industrial Engineering and Production Research, 2021 In the last decade, customers’ active involvement during product development, commonly referred to as co-creation, has emerged as an effective tool to overcome barriers that keep firms from understanding customer needs.
Faisal Rasool +3 more
doaj +1 more source
A model of the supplier involvement in the product innovation [PDF]
Yugoslav Journal of Operations Research, 2017 In this paper we examine the product innovation in a supply chain by a supplier and derive a model for a supplier’s product innovation policy. The product innovation of a supplier can contribute to the long-term competitiveness for the supply ...
Kumar Manoj, Raman Jyoti, Raman Priya
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Competition, Innovation, and Product Exit [PDF]
, 2001 Why do products exit markets? This paper integrates rationale for product exit from a number of different literatures and compares the statistical and substantive effect of these explanations.
de Figueiredo, John, Kyle, Margaret
core
Scientific ReportsDespite much effort, the molecular mechanisms of retinal ganglion cell (RGC) death remain unclear. To identify common cell death-promoting machinery in the mechanically and chemically injured retina, we profiled temporal gene expression patterns and ...
Masaaki Kageyama +2 more
doaj +1 more source
MGIMO Review of International Relations, 2016 The article is dedicated to the study of the models of production of innovations at enterprise and state levels. The shift towards a new technology wave induces a change in systems of division of labour as well as establishment of new forms of cooperation that are reflected both in theory and practice of innovation policy and management.
openaire +5 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source