Results 61 to 70 of about 1,727,218 (301)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Estimation of natural frequency for nonlinear mechanical retention of printed circuit board

open access: yesScientific Reports
Vibrational performance for a structure, in majority of the cases, is estimated/ predicted using frequency domain solvers. Linearity and Time-invariance are imposed onto the structure for solving in frequency domain.
Anurag Arjunan, Arun Babu
doaj   +1 more source

The impact of innovation strategy on organizational learning and innovation performance: do firm size and ownership type make a difference?

open access: yesSouth African Journal of Industrial Engineering, 2016
Though innovation strategy and organizational learning have been credited to impact on product innovation performance, they have been rarely considered in a single model simultaneously.
Beyene, K. T., Shi, C. S., Wu, W. W.
doaj   +1 more source

Product and process innovation and the decision to export. [PDF]

open access: yes
Using data from the Community Innovation Survey for Belgium in two consecutive periods, this paper explores the relationship between firm-level innovation activities and the propensity to start exporting.
Van Beveren, Ilke, Vandenbussche, Hylke
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Comparative analysis of bioactive compounds and physicochemical properties of honeys from Thai local community producer, commercial producers and imported honeys

open access: yesDiscover Food
This study comparatively analyzed 14 honey samples (Thai local, commercial, and imported) for physicochemical properties, sugar composition, and antioxidant activities.
Arusa Chaovanalikit   +2 more
doaj   +1 more source

Product, Process and Organizational Innovation: Drivers, Complementarity and Productivity Effects [PDF]

open access: yes
We propose a model where both R&D and ICT investment feed into a system of three innovation output equations (product, process and organizational innovation), which ultimately feeds into a productivity equation.
George van Leeuwen   +3 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Physicochemical Properties and Nutritional Compositions of Foamed Banana Powders (Pisang Awak, Musa sapientum L.) Dehydrated by Various Drying Methods

open access: yesWalailak Journal of Science and Technology, 2016
The objective of this research was to evaluate the physicochemical properties and nutritional compositions of foamed banana powders, as affected by various drying methods.
Phisut NAKNAEN   +2 more
doaj  

Unionisation structure and product innovation [PDF]

open access: yes
This paper considers the e¤ects of di¤erent labour unionisation structure (viz., decentralised and centralised unions) on product innovation. Although the presence of labour unions reduces the incentive for product innovation compared to the situation ...
Arijit Mukherjee, Debasmita Basak
core  

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