Results 31 to 40 of about 20,116,479 (227)

Innovative design method for a valuable product-service system: concretizing multi-stakeholder requirements

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
As one of the differentiation strategies towards the strained global competitive market, the concept of Product-Service System (PSS) is emerging. Product-Service System (PSS) is a concept of service system, which is represented with functional deliveries
Mar’atus SHOLIHAH, Yuya MITAKE, Takehiko NAKADA, Yoshiki SHIMOMURA   +3 more
doaj   +1 more source

Methods of comparative evaluation of cost and quality of innovative solutions in the project life cycle of high-tech products of mechanical engineering production

Izvestiya MGTU MAMI, 2012
In the article there is considered the technique of comparative evaluation of the cost and quality of high-tech innovation of engineering products at the project preparation stage of production using linear mathematical models. Developed analytical models are descriptive, universal and can be automated with the use of tools of personal computers.
S. V Lukina, M. V Krutyakova, N.P. Solovieva Solovieva, V. V Girko   +3 more
openaire   +1 more source

Data-driven through-life costing to support product lifecycle management solutions in innovative product development [PDF]

, 2011
Innovative product usually refers to product that comprises of creativity and new ideas. In the development of such a new product, there is often a lack of historical knowledge and data available to be used to perform cost estimation accurately.
John D. Lanham, Marsh, Robert, Wai Ming Cheung, Cheung, Wai Ming, Mileham, Antony, Robert Marsh, Newnes, Linda, Linda B. Newnes, Antony R. Mileham, Lanham, John   +9 more
core   +1 more source

COST MEASUREMENT AND COST MANAGEMENT IN TARGET COSTING [PDF]

Annals of the University of Oradea: Economic Science, 2012
Firms are coping with a competitive scenario characterized by quick changes produced by internationalization, concentration, restructuring, technological innovation processes and financial market crisis.
Moisello Anna Maria
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Sectorial Investigation of Life Cycle Sustainability Assessment in the Context of Case Studies

Gazi Üniversitesi Fen Bilimleri Dergisi
The emergence of the concept of sustainability has brought with it the challenge of measuring this concept. Over the years, methods have been developed to assess the environmental impacts of sustainability using Life Cycle Assessment (LCA), evaluate its ...
Seher Demir , Veysel Özdemir
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design to life cycle by value-oriented life cycle costing

, 2022
S.461-466Industrial products basically have to satisfy the customers' wants and needs as a basic input as well as technical and ecological requirements while providing maximum economic benefit throughout the life cycle.
Westkämper, Engelbert, Janz, Danina
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source