Results 131 to 140 of about 145,142 (309)

Openability of tamperproof packaging

open access: yes, 2007
Communication, product protection and presentation are three key aspects in the world of packaging nowadays. Due to a retail landscape consisting of large stores, displaying packed products on the shelves in self-service environments, these aspects ...
Buijs, P.J. (author)   +7 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Consumer Behavior: Product Characteristics and Quality Perception

open access: yes
Consumers rely on signals, both extrinsic and intrinsic attributes, to solve their asymmetric information problem regarding product quality. In this study an experiment is designed to evaluate how consumers assess quality perception in terms of specific ...
Pires Gonçalves, Ricardo
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

How can Ferrum Packaging Ltd. introduce maintenance contracts successfully?

open access: yes, 2021
Ferrum Packaging AG is a manufacturer of can seaming machines based in Switzerland. In order to ensure a long functionality of these machines, the can seaming machines should be maintained and checked regularly.
Freiermuth, Noemi, Gysin, Anna
core  

Platelet Lysate Nusantara (PL-NUSA) Product Packaging Design Using The Nigel Cross Approach

open access: yesDinamika Rekayasa
The health industry is currently developing rapidly. One of the products that is currently developing is Platelet Lysate. Platelet Lysate is an alternative medium for cell growth.
Alfandi Setya Pradana   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Value Creation in PSS Design Through Product and Packaging Innovation Processes [Elektronisk resurs]

open access: yes, 2009
Over the years consumer packaging has become increasingly important as a value-adding element, since packages shape the consumer’s experience with the product during use, as well as accelerate the purchase decision.
Larsson, Andreas,   +2 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Implementing Sustainability Considerations in Packaging Design Curricula

open access: yes, 2018
This study aims to address the structured implementation of sustainability considerations in packaging design processes by proposing a teaching framework for design students.
Mulder-Nijkamp, Maaike   +3 more
core  

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